Acanthosis Nigricans is a condition characterized by discoloration and dark patches in the armpits, neck creases, and other regions. It usually has a velvety appearance. Though it does not have any medical issue, it affects the aesthetic appearance of the person. It is commonly associated with obesity, diabetes, and other lifestyle conditions. Sometimes it is also seen along with a cancerous condition.
- Acanthosis nigricans is not a disease in itself but a symptom, so treating the underlying condition will cure this problem.
- More often, the changes in the blood sugar level and the amount of insulin in the blood is the major cause of this condition.
- People with overweight tend to develop resistance to insulin over time. This creates a buildup of glucose in the bloodstream, which can lead to high levels of both blood glucose and insulin in the bloodstream
- Excess insulin causes skin cells to reproduce at a rapid rate. For people with skin with more pigment, these new cells have more melanin, which causes skin darkening.
- The presence of acanthosis nigricans is a strong predictor of future diabetes.
- Certain medications can trigger acanthosis nigricans, such as: injected supplementary insulin, nicotinic acid, diethylstilbestrol, human, growth hormones, and systemic glucocorticoids.
Cosmetic treatments include
- Skin lighteners like Retin-A, 20 percent urea, alpha hydroxy acids, and salicylic acid
- Topical tretinoin cream
- Oral medications for acne
- Laser therapy
- Maintaining a healthy lifestyle can usually prevent acanthosis nigricans. This includes maintaining weight at a moderate level, managing diet, and adjusting medications contributing to the condition.
Black velvetty symmetric patches on the body
Black discoloration,creaseselvetty patches and outgrowth
Treatments to help with pain and odor, such as skin creams, special soaps,Medications,Laser therapy