Gianotti-Crosti syndrome (GCS), papular acrodermatitis of childhood or acrodermatitis is a rare, childhood skin condition that affects children between the ages of 3 months and 15 years.
- Gianotti-Crosti syndrome is characterized by a papular rash with blisters on the skin of the legs, buttocks, and arms.
- Skin lesions typically last at least 10 days but may last for several weeks. GCS is a response to the underlying infection.
- It has been observed to occur following many viral illnesses and vaccinations.
- If the underlying infection is due to a virus, that in itself is contagious, while papular acrodermatitis is not.
The following can determine your susceptibility to Gianotti-Crosti syndrome(GCS)
Ongoing studies have demonstrated that papular acrodermatitis in childhood can occur following a wide variety of viruses. These viruses include
- Epstein-Barr virus,
- Hepatitis A virus,
- Herpes simplex viruses,
- Parainfluenza virus,
- Parvovirus B19,
- Respiratory syncytial virus, and
Occurrence of CGS has also been reported after vaccination with vaccines for - influenza, Calmette-Guerin bacillus, diphtheria-pertussis-tetanus, poliomyelitis, hepatitis B, Japanese encephalitis, and measles vaccines.
Acute eruption of monomorphic skin-coloured to pink-red papules on the face, buttocks, and extensor surfaces of the extremities,Enlarged lymph glands,Bloated stomach
Formation of benign,Itchy blisters on the body,Children may also develop a bloated abdomen,Fever,Swollen, sore lymph nodes,Hepatitis B, Epstein-Barr or cytomegalovirus (CMV) infection,Acute hepatitis may also occur
1-3 mg/kg of zinc gluconate or sulfate,The majority of cases spontaneously resolve on their own without active intervention,Management of itching by the use of hydrocortisone creams,Antihistamines like Avil can be given