The most effective treatment for mild or moderate dyshidotric eczema is to moisturize your hands or feet with a lotion, cream, or ointment, such a petroleum jelly.
The moisturizer you use should be free of fragrance, dyes, or alcohol.
If allergies are the cause, an over-the-counter (OTC) oral antihistamine should offer some relief.
For itching, try an OTC topical corticosteroid cream (also called a topical steroid or topical cortisone cream), cold compresses, or applications of witch hazel. When self-care doesn't resolve dyshidrotic eczema, your doctor may prescribe a topical cream, such as tacrolimus or pimecrolimus, which suppresses your immune system response.
If your skin condition is severe, your healthcare provider also may prescribe steroid pills, coal tar preparations, phototherapy, or a combination of these.