An accurate diagnosis is crucial to properly inform and counsel parents about epidermolytic hyperkeratosis or epidermolytic ichthyosis (EI). Prenatal diagnosis and genetic counseling are other options.
Infection, secondary sepsis, and electrolyte imbalance are all heightened risks for newborns with epidermolytic ichthyosis who have denuded skin. The neonatal ICU should receive these infants so that it can monitor them and provide any necessary care. To prevent further injury to the skin, they should be handled gently.
- The condition epidermolytic ichthyosis cannot be cured (EI).
- Therapy's main objective is to lessen hyperkeratosis.
- Topical keratolytics such lactic acid, alpha-hydroxy acid, or urea can accomplish this.
- Additionally, topical emollients with glycerin are frequently helpful.
- The patient's age and presentation determine the patient's course of treatment, which is primarily symptomatic.
- To control cutaneous superinfection, electrolyte imbalance, and dehydration, infants in intensive care should be watched closely.
- Broad-spectrum intravenous antibiotics should be used for the treatment of sepsis.
- To preserve the skin and repair denuded regions, topical emollients and cushioning should be applied.
- The decrease of hyperkeratosis is the aim of therapy in both children and adults.
- Improvement in hyperkeratosis has been seen using topical emollients and keratolytic treatments that comprise glycerin, lactic acid, urea, and a-hydroxy acids, although these substances are frequently not well tolerated due to burning and stinging.
- Due to the possibility of developing systemic salicylism, clinicians should refrain from using topical treatments containing higher concentrations of salicylic acid.
Redness of the skin,Babies with red, blistering, and denuded skin at birth, as well as obvious areas of skin thickening,Palmoplantar keratoderma,Palmoplantar keratoderma
Erythroderma,Skin infections,Skin infections,Ichthyosis hystrix
Lactic acid,lpha-hydroxy acid,Urea,Topical emollients,Oral retinoids