Erythrokeratolysis hiemalis is a rare disease associated with palms and soles. When you get affected by this disease, the skin of your palms and soles gets peeled. Itching and postulation happen if someone is affected by this disease. In most cases, the condition is present at the time of birth. But there is also a record of getting the disease during childhood or in adolescent period life.
Risk Factors of erythrokeratolysis hiemalis
- Risk factors of erythrokeratolysis hiemalis are epidermis with focal cellular edema and necrobiosis of the Malpighian layer.
- When clefting occurs in the stratum corneum, the necrobiotic Malpighian layer gets sandwiched in the hyperkeratotic stratum corneum.
- Erythrokeratolysis hiemalis is associated with chromosome 8p22-p23, which is found among the people of South Africa and Germany.
- Since it is an inherited skin disorder, people with the chromosome mentioned above easily get affected by the disease.
- The people residing in South Africa and Germany are at the highest risk of this disease.
- Aggravating factors may include: the winter season, excessive exposure to water, chemicals, or friction, illness, psychological stress, menstruation, secondary bacterial infection, certain medications including topical steroids and general anesthesia, and keratolytic winter erythema can improve in summer and during pregnancy.
Thickness and redness in the skin of palms and soles,Dry blister that cause the peeling of skin from the palms and soles,Shedding skin
Epidermolysis bullosa simplex of hands and feet,keratolysis exfoliative
Vaseline,Epaderm,Topical steroids and retinoids (to control many skin conditions),Topical calciprotriol,Systemic steroids (anti-inflammatory derivatives of cortisol),Photodynamic therapy