About jessner-kanof lymphocytic infiltration

What is jessner-kanof lymphocytic infiltration?

Jessner lymphocytic infiltrate of the skin is an uncommon disorder that is characterized by benign accumulations of lymph cells in the skin. These small lesions are solid, pink or red in color, and appear on the face, neck, and/or back. Skin surrounding these lesions may be itchy and turn red. The lesions may remain unchanged for several years and then spontaneously disappear, leaving no scars.

Not much is known about this disorder. In fact, there is some difference of opinion as to whether it is distinguishable as a separate condition or represents a stage of some other disorder. Some scientists believe that Jessner lymphocytic infiltrate may be a type of lupus erythematosus tumidus (LET) or discoid lupus erythematosus (DLE).

What are the symptoms for jessner-kanof lymphocytic infiltration?

And pimple-like eruptions symptom was found in the jessner-kanof lymphocytic infiltration condition

Patients living with lymphocytic infiltrate of Jessner may experience symptoms including Itchiness (pruritus), Redness of the skin (erythema), and pimple-like eruptions (papules), most commonly on areas exposed to sunlight. These pimple-like Lesions may last up to several months. As they extend from the perimeter, these Lesions form well-defined, smooth, Red patches (plaques) whose diameter may go as far as up to one inch.

Occasionally, clear centers will form on the plaques. The skin surrounding the Lesions may be reddened or itching. Those affected may also experience a Burning sensation surrounding the skin lesions. An additional symptom that people with Jessner disease frequently report is sensitivity of the skin to sunlight exposure cutaneous photosensitivity.

The course of lymphocytic Infiltrate of Jessner varies from person to person. It is important to note that the symptoms typically disappear after several years but it is also possible that they may reappear later. The course or progression of the disease may alternate between periods of worsening and relieving of symptoms. These periods may last up to months or even years in some individuals.

What are the causes for jessner-kanof lymphocytic infiltration?

Lymphocytic Infiltrate of Jessner is a rare inflammatory disease with an unknown cause. What is known however is that this condition involves the inappropriate accumulation of T helper cells (subtype of white blood cells) in the skin. Some clinical scientists argue that this condition is possibly a subtype of the autoimmune condition known as lupus erythematosus, while others believe that it may have its own class.

Jessner disease may have a genetic/hereditary component. In addition, affected individuals may also have a prior history of photosensitivity.

What are the treatments for jessner-kanof lymphocytic infiltration?

Since lymphocytic Infiltrate of Jessner may sometimes resolve on its own, initial recommendation usually includes watchful waiting. In this case, treatment may not be necessary.

Others who may need to seek treatment might be advised to use cosmetics to improve appearance, protect from sunlight, removal of the lesions via surgery, radiotherapy, steroids including topical medium-potency formulations, freezing of the lesions (cryotherapy), the use of select oral medications, or appropriate chemotherapy drugs (cyclophosphamide, methotrexate).

It is important to note that the use of steroids, whether they be topical or systemic, must be monitored very closely. In addition, routine follow-up visits to the dermatologist are essential to monitor overall progress and treatment. Those seeking treatment must also remember to protect from sunlight to prevent progression of existing lesions or formation of new lesions.

What are the risk factors for jessner-kanof lymphocytic infiltration?

An uncommon inflammatory condition called jessner-kanof lymphocytic infiltration has no recognized cause. However, it is understood that this illness is characterized by an abnormal buildup of T helper cells, a subtype of white blood cells, in the skin.

  • There may be a genetic or hereditary component to Jessner's illness. History of photosensitivity may also exist in those who are impacted.
  • Jessner lymphocytic infiltration of the skin (JLIS) still has no identified cause. There are various hypothesized etiologies, though.
  • Given the numerous familial cases of the disease that have been described, there may be a genetic or hereditary component.
  • Autoimmune factors are another potential cause. It is well recognized that the plasmacytoid dendritic cells found in JLIS contribute to autoimmune conditions such as systemic lupus erythematosus.
  • JLS may be an early cutaneous sign of SLE or perhaps a development of lupus erythematosus timidus, according to one theory.
  • Some researchers think that the lymphocytic infiltrate of Jessner affects more men than women, despite the fact that its frequency in the United States or Europe is not yet fully established.
  • Additionally, it rarely affects youngsters and typically develops between the ages of thirty and fifty.

Itchiness, redness of the skin, and pimple-like eruptions, most commonly on areas exposed to sunlight
Pruritus,Erythema,Cutaneous photosensitivity
Surgery,Radiotherapy,Steroids,Chemotherapy drugs (cyclophosphamide, methotrexate)

Is there a cure/medications for jessner-kanof lymphocytic infiltration?

Jessner lymphocytic infiltration of the skin/jessner-kanof lymphocytic infiltration is a rare disease that is very uncommon. It is characterized by gentle accumulations of lymph cells in the skin, which results in small regions in the skin that are solid and reddened colored, which appear on the face, neck and backside. These lesions may appear for several years unchanged, but after that, they disappear.

  • There is no particular therapy for the Jessner lymphocytic infiltration of the skin (JLIS).
  • Sometimes, this disease will resolve over time; in that case, the disease symptoms tracking and wait and watch theory is useful initially, because treatments are not required in some cases,
  • Cosmetics are used for good appearance, protection from sunlight, radiotherapy, and removal of patches via surgery.
  • Some oral medicines or chemotherapy drugs are useful for this disease.
  • Topical or systemic steroids are useful for the treatments. Since it is risky so it needs to be monitored carefully.
  • In topical steroids, current treatments involve the use of hydrocortisone, triamcinolone, betamethasone, and prednisone, or antimalarials like hydroxychloroquine, but they have their own side effects.
  • Also, Tacrolimus, thalidomide, etretinate, methotrexate, oral auranofin, and proquazone are involved in the therapy, and they are beneficial too, as per studies.
  • Cosmetic camouflage, photoprotection, and excision of small lesions can be useful for treatments, and other therapies are laser therapy, photodynamic therapy, and cryotherapy for treatment.

Itchiness, redness of the skin, and pimple-like eruptions, most commonly on areas exposed to sunlight
Pruritus,Erythema,Cutaneous photosensitivity
Surgery,Radiotherapy,Steroids,Chemotherapy drugs (cyclophosphamide, methotrexate)

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