Keratolytic winter erythema is distinguished by cyclical patchy redness and skin thickening of the palms and soles, which is followed by the formation of dry blisters that peel in an extending pattern. A thickish peel covers the losing skin. The exposed surface skin looks to be glazed. These symptoms normally occur during infancy or youth, and the disease improves with maturity.
- KWE is inherited in an autosomal dominant manner, with males and females equally afflicted. It was discovered to be linked to the duplication of a chromosomal region containing an enhancer element.
- One in every 7,200 white Afrikaans speakers is thought to have keratolytic winter erythema.
- It is passed down in a monogenic autosomal dominant manner with strong penetrance but variable expressivity.
- It is most commonly found in childhood or early adulthood.
Among the aggravating factors are:
- The winter months
- Excessive water, chemical, or friction exposure
- Stress on the mind
- Bacterial secondary infection
- Topical steroids and general anaesthesia are examples of drugs.
Redness of skin or mucous membrane,Abnormal excessive perspiration,Skin pustules