Necrotizing fasciitis (flesh-eating disease) progresses rapidly and can result in death hence an early diagnosis and providing appropriate treatment is of utmost importance.
- Early medical treatment is often presumptive; antibiotics should be started as soon as this condition is suspected.
- Surgical debridement is the standard treatment for necrotizing fasciitis.
- Aggressive Necrotizing fasciitis should be performed early, usually as soon as the diagnosis is made.
- Empiric antibiotics are usually initiated as soon as the diagnosis of NSTI has been made. Culture-guided antibiotic therapy is later made.
- Moxifloxacin (a fluoroquinolone) and amoxicillin-clavulanate (penicillin) and evaluated the appropriate duration of treatment (varying from 7 to 21 days); however, no definitive conclusions on the efficacy of treatment, could be made.
- Supportive therapy, often including intravenous hydration, wound care, anticoagulants to prevent thromboembolic events, pain control, etc., are needed.
Severe pain,Purple colored skin in the affected area,Pain in the affected area,Intense pain out of proportion to the signs of the local skin infection,Erythema,Tenderness,Heat,Fever and other flu-like symptoms,Swelling of the painful area,Diarrhea,Vomiting
Swelling and intense pain,Ischaemia with blisters and bullae,Hypoxia,Edema and ecchymoses,Fever
Use of broad-spectrum antibiotics: Ampicillin or ampicillin–sulbactam combined with metronidazole or clindamycin, Metronidazole, carbapenems, doxycycline and minocycline,Surgical management to limit the spread of infection: surgical debridement, necrosectomy, and fasciotomy are the main features of surgical treatment.