Von Zumbusch Disease is characterized by cutaneous lesions, inflammation, and tissue damage (necrosis) of blood vessel walls (lumen).
- Before beginning treatment, it's crucial to ascertain whether there is an underlying condition that contributes to the Von Zumbusch Disease.
- The term "vasculitides" or "vasculitic syndromes" refers to a larger class of diseases that affect blood vessels and inflammation.
- Von Zumbusch Disease is one of these diseases. These syndromes range from minor skin-only conditions to more serious ones that may affect several organ systems.
- The results of a skin biopsy show whether or not Von Zumbusch Disease is present.
- Additional tests of other organ systems must be recommended in order to confirm that Von Zumbusch Disease is restricted to the skin because some of the more severe vasculitides affect the skin in addition to other organ systems.
Treatment for the Von Zumbusch Disease
- The cause and symptoms of Von Zumbusch Disease determine the course of treatment. The symptoms of this disorder can typically be treated by getting rid of the irritating factor (such as medicine) and taking care of the underlying infection.
- It has been demonstrated that the medications prednisone, cyclophosphamide, pentoxifylline, and azathioprine are effective in treating the autoimmune form of Vasculitis.
- Other forms of treatment are supportive and symptomatic.
Skin lesions may be flat and red (macules),Nodules or more substantial hemorrhages under the skin (purpura),Occur mostly often on the back, hands, buttocks, the inside areas of the forearm and the lower extremities
Wheal-like lesions that cause intense itching (urticaria),Ring-shaped lesions and ulcers,Blister-like lesions (vesicles, bullae), fever, generalized discomfort (malaise),Muscle or joint pain