Acanthosis nevus syndrome is much more severe than the acanthosis nigricansTreatment course-The treatment of this condition is a combination of cosmetic therapy and surgeries accompanied by the treatment for the underlying cause of the disease. This improves both the appearance and theThe standard therapy for epidermal nevi is surgery or ablative CO2 laser treatment.Topical tretinoin c  Read More

Argyria is a rare condition that causes the skin to turn blue or grey. This discolouration happens when the body comes into contact with excessive amounts of silver.There is no defined treatment for this disease. It can be treated by the restriction of the underlying cause.This could be the use of colloidal silver therapy, hydroquinone usage for skin conditions, silver dental fillings etc.When the  Read More

Chikungunya is a rare viral infection transmitted by the bite of an infected mosquito. It is characterized by a rash, fever, and severe joint pain (arthralgias) that usually lasts for three to seven days. Because of its effect on the joints, Chikungunya has been classified among the Arthritic Viruses. It primarily occurs in tropical areas of the world.  Read More

Atopic dermatitis facts Atopic dermatitis is a type of eczema. The disease may be inherited and genetically determined. The patient's skin may be "super sensitive" to many irritants. Dry, scaly patches develop in a characteristic distribution. Itching varies but may be intense and scratching hard to resist. Scratching can cause skin thickening and darkening and lead to further co  Read More

Auriculotemporal syndrome or the Frey syndrome is a postoperative phenomenon following salivary gland surgery and also in neck dissection, facelift procedures, and trauma that is characterized by excessive sweating and flushing.The previous sympathetic responses of sweating and flushing are now controlled by postganglionic parasympathetic fibers.Mastication, which releases acetylcholine from the parasympat  Read More

Black tongue, in most cases, resolves by regularly brushing your tongue with a toothbrush.Medications:Your doctor may also prescribe a topical retinoid medication to help increase cell turnover on your tongue.For stubborn elongated papillae, a doctor can remove them using carbon dioxide laser burning or electrodesiccation, which simultaneously cuts and seals the papillae.Cure throu  Read More

Bloom syndrome is a rare genetic disorder characterized by short stature; increased sensitivity to light (photosensitivity); multiple small dilated blood vessels on the face (facial telangiectasia), often resembling a butterfly in shape; immune deficiency leading to increased susceptibility to infections; and, perhaps most Importantly, a markedly increased susceptibility to cancer of any organ, but especially to leukemia and lymphoma. Some cli  Read More

Bloom syndrome is a rare genetic disorder characterized by short stature; increased sensitivity to light (photosensitivity); multiple small dilated blood vessels on the face (facial telangiectasia), often resembling a butterfly in shape; immune deficiency leading to increased susceptibility to infections; and, perhaps most Importantly, a markedly increased susceptibility to cancer of any organ, but especially to leukemia and lymphoma. Some cli  Read More

Blue rubber bleb nevus syndrome (BRBNS) is a rare blood vessel (vascular) disorder that affects the skin and internal organs of the body. Multiple distinctive skin lesions are usually characteristic of this disorder and are often present at birth or present during early childhood. Lesions in the gastrointestinal tract frequently become apparent during childhood or early adulthood. The lesions are multifocal venous malformations, resulting from  Read More

Boils (skin abscesses) if they are small, can generally be treated at home by applying warm compresses to relieve pain and promote natural drainage. In severe cases, medications and further treatment may be needed.Apply warm compresses and heated water to a boil. In addition to bringing the pus to the surface, this will lessen the pain.When the boil reaches its peak, repeated soaks will cause it to rupture  Read More

Bullous pemphigoid is a rare skin condition that causes large, fluid-filled blisters. They develop on areas of skin that often flex - such as the lower abdomen, upper thighs or armpits. Bullous pemphigoid is most common in older adults.TreatmentFor moderate-to-severe cases of bullous pemphigoid, your healthcare provider may prescribe an oral corticosteroid, like prednisone in addition to a steroid-spari  Read More

Carate, also known as Pinta, is a skin disease caused by a spiral-shaped bacterium called Treponema Carateum.The signs and symptoms of Carate are as follows:Carate only affects the skin. It begins as itchy, flat, reddened areas on the arms, hands, face, feet, legs, or neck.These affected areas enlarge and thicken; however, after several months, some three to nine months later, further thickened  Read More

Chanarin - Dorfman disease doesn't have any effective cure still, it can be managed in the following ways:A low-fat diet for the minimum accumulation of fat in the body. Moreover, it is recommended to get a dietician for the feeding process of your child.Having a low-fat diet, enriched with medium-chain triglycerides, ursodiol (a bile acid), and vitamin E, would decrease the liver size and normalize the li  Read More

Chickenpox is a viral infection caused by the varicella-zoster virus that causes small fluid-filled itchy blisters and rash on the skin along with fever, headache, and fatigue. Chickenpox has three stages first, it will cover the entire body in the form of red bumps, then it changes its forms into small fluid blisters, and finally, these blisters burst, crust, and scabs cover it. These crusts eventually heal in a few days. How  Read More

Congenital or Child Naevus (moles) generally don't cause problems unless they show cancerous signs.Cure/medications include:Your child's doctor will need to check the mole over time to watch for any changes that may signal a future risk of skin cancer.On the other hand, if you worry about the mole's appearance or location, you can talk to your doctor about removal.Discussing with the d  Read More

Contact dermatitis usually occurs on areas of your body that have been directly exposed to the reaction-causing substance — for example, along a calf that brushed against poison ivy or under a watchband. The rash usually develops within minutes to hours of exposure and can last two to four weeks. Signs and symptoms of contact dermatitis include: A red rash Itching, which may be severe Dry, crack  Read More

Cross-McKusick-Breen Syndrome, Oculocerebral Syndrome with Hypopigmentation, Cross Syndrome, Depigmentation-Gingival Fibromatosis-Microphthalmia or Kramer Syndrome is an extremely rare inherited disorder characterized by the lack of normal color of the skin and hair.The skin lacks melanin and as a result, is extremely sensitive to exposure to the sun.It is also associated with impaired vision, breathing di  Read More

Cutis laxa encompasses a group of rare disorders that occur in several inherited congenital forms or are acquired at some point during life -acquired cutis laxa. Cutis laxa involves a wide spectrum of symptoms that result from defects in connective tissue found throughout the body - in muscles, joints, skin and other organs.The treatment of Cutis laxa focuses on managing the symptoms and treating other conditions.  Read More

De Barsy syndrome is a rare, autosomal recessive genetic disorder, the main characteristics of which are a prematurely aged-looking face (progeria), cloudy corneas, short stature, and mental retardation. The condition is expressed in variable presentations involving complicated patterns of ocular, facial, skeletal, dermatologic and neurological abnormalities.  Read More

Darier disease, also called keratosis follicularis, is a genodermatosis. It is a rare genetic disorder inherited in an autosomal dominant manner.The responsible mutations occur in the gene that encodes the calcium pump, in the endoplasmic reticulum.The keratinocytes in the skin of the affected person lose cohesion among themselves, which leads to the manifestations.The classic features of the dise  Read More

De Barsy syndrome is a rare, autosomal recessive genetic disorder, the main characteristics of which are a prematurely aged-looking face (progeria), cloudy corneas, short stature, and mental retardation. The condition is expressed in variable presentations involving complicated patterns of ocular, facial, skeletal, dermatologic and neurological abnormalities.  Read More

De Barsy syndrome is a rare, autosomal recessive genetic disorder, the main characteristics of which are a prematurely aged-looking face (progeria), cloudy corneas, short stature, and mental retardation. The condition is expressed in variable presentations involving complicated patterns of ocular, facial, skeletal, dermatologic and neurological abnormalities.  Read More

In most cases, the initial symptoms of Degos disease are distinct skin lesions or a rash. Affected individuals develop small elevated bumps or spots (papules) of varying shape, usually on the trunk and upper arms and upper legs. Initially, only a few lesions may be apparent. Eventually, 10-40 lesions may slowly develop and, in some cases, hundreds may develop. The palms, soles, and face are usually spared. The lesions may sometimes itch (pruri  Read More

Sjogren-Larsson syndrome is an inherited disorder characterized by scaling skin (ichthyosis), mental retardation, speech abnormalities, and spasticity. Affected infants develop various degrees of reddened skin with fine scales soon after birth. After infancy, the skin loses its redness and dark scales often appear on the neck and under the arms. Additionally, larger plate-like thick scales may develop on the lower legs. Developmental delay, sp  Read More

Harlequin syndrome is a rare disorder of the autonomic nervous system. The blockage results in hemifacial discoloration, sharply demarcated at the midline. It is a self resolutive disease.Treatment/ managementThough Harlequin syndrome may not need treatment, in cases where the individual may feel socially embarrassed, contralateral sympathectomy may be considered.In this treatment, the nerve bu  Read More

Dermatitis herpetiformis, also known as Duhring disease, is a rare, chronic, skin disorder characterized by the presence of groups of severely itchy (pruritic) blisters and raised skin lesions (papules). These are more common on the knees, elbows, buttocks and shoulder blades. The exact cause of this disease is not known although it is frequently associated with the inability to digest gluten (gluten sensitive enteropathy [GSE] or celiac sprue  Read More

The treatment of dyskeratosis follicularis vegetans or Darier's disease (DD) is directed toward the specific symptoms that are apparent in each individual. Aside from symptom management and behavioral modifications to avoid triggers, currently, no validated treatments for dyskeratosis follicularis vegetans are available.Symptomatic treatments include:Sunscreen, loose clothing, moisturizing creams and av  Read More

E-d syndrome is known as Ehlers- Danlos syndrome, EDS, or elastic skin. This is a type of disorder that mainly affects connective tissue. It is basically a genetic disorder.E-d syndrome is a dominant or recessive genetic condition.E-d syndrome occurs when only a single copy of an abnormal gene is inherited from either parent or can be the result of a new mutation (gene change) in the affected individual.  Read More

Atopic dermatitis or eczema may last for years. To control it, you might need to try a variety of medications over the course of months or years. Additionally, even after successful therapy, signs and symptoms could come back (flare).Early diagnosis of the illness is crucial in order to begin treatment. Your doctor might advise one or more of the following therapies if routine moisturizing and other self-care pract  Read More

Ehlers- Danlos syndrome, EDS, or elastic skin, is a type of disorder that mainly affects connective tissue. It is basically a genetic disorder.E-d syndrome is a dominant or recessive genetic condition.E-d syndrome occurs when only a single copy of an abnormal gene is inherited from either parent or can be the result of a new mutation (gene change) in the affected individual.There are 50% chance of  Read More

Empeines, also called Pinta, is a disease that is very rare and spread by infections that affect the skin. Pinta is a disease which affected by Treponema carateum bacteria, which is spiral-shaped bacteria. This also causes diseases like yaws, and syphilis.This disease is transmitted by direct skin-to-skin contact and nonsexual contact.The disease does not affect other body organs, but it affects exposed ar  Read More

Epidermal nevi or epidermal nevus syndrome are harmless, hamartomatous skin growths that appear at birth or evolve in childhood. They are regarded to be a type of cutaneous mosaicism since they are made up of a variety of epidermal cells and structures, such as keratinocytes, smooth muscle cells, hair follicles, apocrine and eccrine glands, and sebaceous glands.Epidermal nevus syndromes are a set of rare complicate  Read More

Epidermolysis bullosa acquisita is an uncommon autoimmune blistering disorder characterized by tight subepithelial blisters at trauma sites. Epidermolysis bullosa acquisita, unlike Epidermolysis bullosa, is not hereditary and usually manifests in adulthood.Epidermolysis bullosa acquisita blisters are typically found in vulnerable locations like the hands, feet, elbows, knees, and buttocks. Mucosal involvement occas  Read More

An accurate diagnosis is crucial to properly inform and counsel parents about epidermolytic hyperkeratosis or epidermolytic ichthyosis (EI). Prenatal diagnosis and genetic counseling are other options.Infection, secondary sepsis, and electrolyte imbalance are all heightened risks for newborns with epidermolytic ichthyosis who have denuded skin. The neonatal ICU should receive these infants so that it can monitor th  Read More

Cells that have Epiloia cease dividing when they ought to. This means that many parts of your body can develop tumours. While they are not cancerous, the areas where they are growing may experience issues. There are Treatments available that can reduce the tumours and increase your comfort.Cure or medications for EpiloiaIn case of seizures, anti-seizure medications may be prescribed. Other medications m  Read More

The erythema multiforme rash The EM rash can consist of dozens of target-shaped (bull’s-eye pattern) lesions that develop over a 24-hour period. These lesions can start on the backs of hands and tops of feet before spreading to the trunk. They may also develop on the face and neck. The arms may be more affected than the legs. These lesions can be concentrated  Read More

Erythropoietic protoporphyria (EPP) is a rare inherited metabolic disorder characterized by a deficiency of the enzyme ferrochelatase (FECH). Due to abnormally low levels of this enzyme, excessive amounts of protoporphyrin accumulate in the bone marrow, blood plasma, and red blood cells. The major symptom of this disorder is hypersensitivity of the skin to sunlight and some types of artificial light, such as fluorescent lights (photosensitivit  Read More

Type 1 Classic Phenotype The signs and symptoms of males with the type 1 classic phenotype typically begin in childhood or adolescence (Desnick 2001, Desnick and Brady 2004). Symptoms increase with age primarily due to the progressive glycolipid accumulation in the micro-vascular system, kidney podocytes, and cardiomyocytes leading to kidney insufficiency and failure, heart disease, and/or strokes. Early and progressive clinical sympto  Read More

Skin peeling syndrome or familial continuous skin peeling happens on its own, is painless, and can last a lifetime while gradually getting better. Like skin peeling after a severe sunburn, affected people and/or their caretakers might frequently manually remove sheets of skin.Applying skin-softening (emollient) ointments to treat peeling skin syndrome, particularly after a bath when the skin is moist, may provide s  Read More

Folliculitis signs and symptoms include: Clusters of small red bumps or white-headed pimples that develop around hair follicles Pus-filled blisters that break open and crust over Itchy, burning skin Painful, tender skin A large swollen bump or mass When to see a doctor Make an appointment with your doctor if your condition is widespread or the signs and symptoms d  Read More

Formaldehyde Poisoning is a disorder brought about by breathing the fumes of formaldehyde. This can occur while working directly with formaldehyde, or using equipment cleaned with formaldehyde. Major symptoms may include eye, nose, and throat irritation; headaches; and/or skin rashes.  Read More

Formaldehyde Poisoning is a disorder brought about by breathing the fumes of formaldehyde. This can occur while working directly with formaldehyde, or using equipment cleaned with formaldehyde. Major symptoms may include eye, nose, and throat irritation; headaches; and/or skin rashes.  Read More

A skin condition that occurs in sweat-producing areas is known as Fox Fordyce Disease. It is a rare condition that mainly occurs in women between the age of 13 to 35 years. Areas affected by the disease have itchy bumps produced around the hair follicles of the underarm, nipples, and other pubic regions.The ratio of women to men with the disease is more due to sweat accumulation and bacterial production. It is due  Read More

The diagnosis of Fraser syndrome is made based on physical examination and medical history.There is currently no cure for Fraser syndrome.Treatment of FS may include surgery to correct the physical deformities.Other treatments are is symptomatic and supportive.A team of specialists must evaluate each patient and determine ways to treat the symptoms.However, it should be noted tha  Read More

The severe form of the disease is called typical mucolipidosis IV, and the mild form is called atypical mucolipidosis IV. Approximately 95 percent of individuals diagnosed with this condition have the severe form. The symptoms and physical findings associated with mucolipidosis IV are usually apparent within three to eight months following birth. The first recognized symptoms are usually clouding (opacity) of the cornea and eye movemen  Read More

The Giroux Barbeau syndrome is also called Erythrokeratodermia with ataxia.This disease is caused by pathogenic variants in any of the gens that occur at random patterns or by hereditary patterns. In hereditary patterns, there are autosomal dominant or autosomal recessive patterns. In the autosomal dominant pattern, a single copy of the non-working gene can cause the disease; this non-  Read More

Fabry disease is a rare genetic disorder of fat (lipid) metabolism characterized by a deficiency of the enzyme alpha-galactosidase A (previously known as ceramide trihexosidase). The disorder belongs to a group of diseases known as lysosomal storage disorders. Lysosomes function as the primary digestive units within cells. Enzymes within lysosomes break down or digest particular compounds and intracellular structures. Alpha-galactosidase funct  Read More

Symptoms of mycosis fungoides can look like symptoms of some common and less serious skin conditions, like eczema or psoriasis. Since mycosis fungoides usually worsens very slowly, it may look like a skin rash or scaly patch of skin for years or even decades. Because of this, people with this skin cancer may at first be misdiagnosed as having another skin condition. If you have mycosis fungoides, your symptoms will vary dependi  Read More

Grover’s disease can usually be treated using topical medications, but sometimes requires oral medication, injections, or light therapy to treat it.Cortisone cream: Your dermatologist will prescribe you a cortisone cream if you have a small blister or outbreak that doesn’t itch.Tetracycline: If you have larger outbreaks that itch and cover the entire trunk, your dermatologist may prescribe the  Read More

Lichen Planus is a rare, recurrent, itchy rash or area of inflammatory eruptions (lesions) of unknown origin characterized by shiny reddish-purple spots on the skin and gray-white ones in the mouth. The disorder may present as itchy spots on the wrist, legs, torso, genitals, mouth, or lips. The eruptions may appear as small separate, angular spots that may coalesce into rough scaly patches. This disorder is frequently accompanied by oral lesio  Read More

Guttate scleroderma is one of the abandoned names of a skin disease, currently called lichen sclerosis (LS). It is a chronic, inflammatory, mucocutaneous disorder of genital and extra-genital skin.The exact etiology has not been established. Some of the causes include autoimmune abnormalities, genetic factors, hormonal influence, and infections.In the early stages, symptoms include luminal hyperkeratosis a  Read More

Gottron syndrome (GS) is an extremely rare inherited disorder characterized by the appearance of premature aging (progeria), especially in the form of unusually fragile, thin skin on the hands and feet (distal extremities). GS is described as a mild, nonprogressive, congenital form of skin atrophy due to the loss of the fatty tissue directly under the skin (subcutaneous atrophy). Other findings may include abnormally small hands and feet with  Read More

Pallister-Hall syndrome (PHS) is an extremely rare genetic disorder that is typically apparent at birth. The symptoms and findings associated with the disorder may vary greatly in range and severity from patient to patient. However, in many individuals with PHS-associated abnormalities may include the presence of extra fingers and/or toes; an abnormal division of the epiglottis (bifid epiglottis); a malformation of the hypothalamus (hypothalam  Read More

A genetic skin condition called hallopeau-siemens disease or dystrophic epidermolysis bullosa causes blisters to grow. One of the more severe types is the Hallopeau-Siemens syndrome type.Due to the defect's location in the dermis at the dermo-epidermal junction, even little skin trauma results in profuse blister production that always heals with scars.Anchoring fibrils are either absent or inadequate due t  Read More

Harley syndrome or Harlequin syndrome is a rare dysautonomic syndrome caused by the unilateral blockade of the T2-T3 fibers carrying sudomotor and vasomotor supply to the face.The autonomic nervous system is responsible for regulating the natural processes of the body, including sweating, skin flushing, and the response of the pupils to any stimuli. The exact cause of the condition is not found yet.The sym  Read More

Several over-the-counter or prescription medications are used to treat heat rash also known as prickly heat, sweat rash, or miliaria rubra.Ointments: Ointments like calamine lotions are recommended to treat the symptoms of heat rash, since calamine lotions have a number of benefits for the skin, partly because it contains zinc oxide. It helps treat heat rash by soothing itchiness. Take some calamine lotion in a cot  Read More

Usually, hematoma underneath the skin and within soft tissues such as muscles can be treated at home using the following methods:Elastic bandages help to keep swelling at bay.Elevating the affected area to alleviate swellingUsing ice packs multiple times each day for the first 24 to 48 hours to minimize swelling and soreness.Warm compresses after 2 days of ice to aid in the fluid's absorp  Read More

Hereditary Spherocytosis (HS) is a red blood cell disorder caused by a genetic mutation. Though there is no cure for this disorder, there are certain treatment options available depending on the severity of the condition.The treatments for Hereditary Spherocytosis (HS) are as follows:To slow the breakdown of red blood cells, a total or partial Splenectomy (surgical removal of the spleen) is recommended based  Read More

The most common symptom of angioedema is swelling with a red colored rash beneath the surface of the skin. It may occur in a localized area on or near the feet, hands, eyes, or lips. In more severe cases, the swelling can spread to other parts of the body. Angioedema may or may not be accompanied by swelling and welts on the surface of the skin. Additional symptoms of angioedema may include abdominal cramping. In rare cases, pe  Read More

Cowpox is a viral disease that normally affects the udders and teats of cows. On rare occasions, it may be transmitted to humans and produce a characteristic red skin rash and abnormally enlarged lymph nodes (lymphadenopathy). Cowpox is caused by the vaccinia virus and has been known to cause systemic reactions (generalized vaccinia) in some people who have been recently vaccinated against cowpox.Cowpox produces immunity to smallpo  Read More

There is no cure available for Keratosis follicularis spinulosa decalvans (KFSD).Treatments include:Applying skin-softening (emollient) ointments to soften and add moisture to the skin helps KFSD patients with their dry, itchy skin. This can be especially effective after bathing while the skin is still moist.Plain petroleum jelly and Lactate lotion is also said to be effective and is preferable  Read More

Newborns with Netherton syndrome have reddened skin (erythroderma) and sometimes a thick parchment-like covering of skin (collodion membrane). The skin is red and scaly all over. Hair shafts are fragile and break easily due to trichorrhexis or “bamboo hair”, resulting in short sparse hair. In older children and adults the scaling may have a distinctive circular pattern (ichthyosis linearis circumflexa). Another characteristic of Ne  Read More

Sjogren-Larsson syndrome is an inherited disorder characterized by scaling skin (ichthyosis), mental retardation, speech abnormalities, and spasticity. Affected infants develop various degrees of reddened skin with fine scales soon after birth. After infancy, the skin loses its redness and dark scales often appear on the neck and under the arms. Additionally, larger plate-like thick scales may develop on the lower legs. Developmental delay, sp  Read More

Ichthyosis Vulgaris is caused by an inherited genetic flaw, a mutation that affects a large protein called filaggrin.The faulty gene is inherited from one's parents and may be caused by one or more mutations in the profillagrin gene that occur early in fetal development.It is autosomal dominant, which means that all that is required for the condition is a single faulty copy of the gene that codes for f  Read More

Impetigo is a commonly transmitted skin infection. Bacteria such as Staphylococcus aureus and Streptococcus pyogenes infect the epidermis, or outer layers of the skin. The face, arms, and legs are the most commonly affected areas.Impetigo can affect anyone, although it is more frequent in children, particularly those aged 2 to 5.Minor cuts, bug bites, or a rash like eczema — any spot where the skin is damaged  Read More

Specific treatment for incontinentia pigmenti has not yet been described. However, the management of the disease requires a multidisciplinary approach and needs consultation with different specialists from time to time.Lesions appear within a few months from birth but disappear by adolescence. However, the lesions recur and require to be managed.All stage lesions must be kept cool and dry.The patients develop hypo  Read More

Intertrigo is a rash that typically affects the creases of the skin, areas where the skin brushes together, or areas where the skin is frequently moist. This rubbing can create a breakdown in the skin's top layers, resulting in irritation and a rash.The disintegration of skin facilitates the development of germs or fungus in this location. It may aggravate the rash.Intertrigo is especially common in overwe  Read More

The precise cause for Ito hypomelanosis is unknown.Genetic mosaicism and spontaneous gene mutations are linked to several occurrences.The term "genetic mosaicism" refers to people who established two separate cell lines in their bodies as a result of a gene mutation that happened during embryonic development. •Chromosome discrepancies exist between the two cell lines (chromosomal mosaicism).  Read More

An uncommon inflammatory condition called jessner-kanof lymphocytic infiltration has no recognized cause. However, it is understood that this illness is characterized by an abnormal buildup of T helper cells, a subtype of white blood cells, in the skin.There may be a genetic or hereditary component to Jessner's illness. History of photosensitivity may also exist in those who are impacted.Jessner lympho  Read More

Jock itch usually begins with a reddened area of skin that spreads out from the crease in the groin in a half-moon shape onto the upper thigh. The border of the rash may consist of a line of small, raised blisters. The rash often itches or burns, and the skin may be flaky or scaly. When to see a doctor See your doctor if you have a rash on your skin that doesn't improve within two weeks or if you treat it with over-the-counte  Read More

Johnson –stevens disease is a very rare syndrome with potentially fatal skin reactions in which loss of skin occurs and mucosal membranes accompanied by systemic symptoms is shown in some case. For these conditions, in 80% of cases, the reactions from medications are responsible.This condition requires intensive care or burn care unit in hospitalization,If a person is taking unessential medication  Read More

Kabuki Make-up Syndrome is also known as Niikawa-Kuroki Syndrome or KMS. It is a rare congenital disorder. This affects various parts of the body but mainly the face. It is so rare that one case is reported among 32,000 births.There arise multiple abnormalities, and they can become apparent with the growing age of the child. A child having kabuki makeup syndrome may have the following characteristics-Pa  Read More

Keratitis ichthyosis deafness (KID) syndrome is a rare, genetic, multi-system disorder. It is characterized by defects of the surface of the corneas (keratitis), red, rough thickened plaques of skin (erythrokeratoderma) and sensorineural deafness or severe hearing impairment. The skin on the palms of the hands and soles of the feet and the nails may be affected. KID syndrome belongs to a group of skin disorders marked by dry, scaly skin known  Read More

The Koebner disease or phenomenon affects persons who have specific skin conditions, most often psoriasis. It can occur in persons who have warts, vitiligo, or lichen planus. An accident, cut, or burn might result in new lesions that seem similar to the initial skin illness.There is no known treatment for the Koebner phenomena.Treatment is usually the same because the phenomenon is essentially an extens  Read More

If you're allergic to latex, you're likely to have symptoms after touching latex rubber products, such as gloves or balloons. You can also have symptoms if you breathe in latex particles that are released into the air when someone removes latex gloves. Latex allergy symptoms range from mild to severe. A reaction depends on how sensitive you are to latex and the amount of latex you touch or inhale. Your reaction can become worse with ea  Read More

Launois-Bensaude syndrome is a rare condition consisting of adipose masses symmetrically. It is distributed mainly in the upper part of the body. a condition marked by symmetrical, painless diffuse fat deposits under the skin of the arms, legs, upper trunk, and neck.Though its specific mode of inheritance is unknown, the ailment is believed to be genetic; it could be a mitochondrial DNA disease. This condition usually co  Read More

A chronic inflammatory disorder that affects the skin and mucosal membranes is Lichen Annularis.Inflammation (swelling and irritation) on the skin or within the mouth is a common symptom of lichen planus.Your skin develops an itchy rash as a result of Lichen Annularis.Your mouth may become painful or burn.An unidentified protein in the skin and mucosal keratinocytes is the target of infla  Read More

Lichen planus facts Lichen planus is a chronic recurrent rash of unknown cause with no established cure. Lichen planus generally affects adults and can involve any portion of the body, but it has a predilection for the wrists, ankles, and oral and genital tissues. Lichen planus can be quite itchy. Lichen planus may spontaneously resolve. Lichen planus is managed with a variety of topical a  Read More

Lichen Planus is a rare, recurrent, itchy rash or area of inflammatory eruptions (lesions) of unknown origin characterized by shiny reddish-purple spots on the skin and gray-white ones in the mouth. The disorder may present as itchy spots on the wrist, legs, torso, genitals, mouth, or lips. The eruptions may appear as small separate, angular spots that may coalesce into rough scaly patches. This disorder is frequently accompanied by oral lesio  Read More

A rare, chronic skin ailment called Lichen Psoriasis causes small patches of skin to thin down and turn colourless. Any region of the body can be affected, although the skin around the genitals is most frequently affected. Men and children can occasionally develop Lichen Psoriasis, although most occurrences afflict women who have undergone menopause.The proper medical care can manage Lichen Psoriasis. Here are the  Read More

Sometimes, mild cases of lichen sclerosus cause no noticeable signs or symptoms. When they do occur, lichen sclerosus symptoms may include: Itching (pruritus), which can be severe Discomfort or pain Smooth white spots on your skin Blotchy, wrinkled patches Easy bruising or tearing In severe cases, bleeding, blistering or ulcerated lesions Painful intercourse  Read More

Lichen Urticatus is the most common childhood skin condition. It is distinguished by itchy and irritating red blotches or hives.It is caused by a hypersensitive allergic reaction to insect bites, drugs, food, plants, and prolonged sun exposure.Hives are characterized by raised red splotches that itch or burn and can range in size from small dots to large patches covering multiple areas of your body at the  Read More

Lipoma is usually painless and harmful, but if it is bothering you, or growing further, then it needs to be removed.Lipoma treatments include:Surgical removal: Lipomas are mostly removed through surgery by cutting them out. However, there are chances that they may occur again. Since the surgery may leave a scar or get the area bruised, minimal excision extraction may be performed so that it results in l  Read More

Localized Epidermolysis bullosa simplex (EBS) is a genetic disease, which means that it is caused by one or more genes not working correctly.The majority of EBS subtypes are inherited in a dominant manner. This means that an affected parent passes them on to half of his or her offspring. EBS affects both men and women equally.Epidermolysis bullosa simplex is often transmitted in an autosomal dominant manne  Read More

Malignant atrophic papulosis is an uncommon vasculopathy that affects the skin, gastrointestinal tract, and nervous system. The systemic variant has a rapid clinical course and a high death rate.TreatmentThere is no effective treatment for atrophic papulosis. Anticoagulants and blood perfusion drugs such as acetylsalicylic acid, pentoxifylline, dipyridamole, ticlopidine, and heparin have achieved partial regr  Read More

Melanoma is a type of cancer. It may also be called malignant melanoma or cutaneous melanoma. Most melanomas are brown and black, but they can also be pink, tan, or even white. There are four main types of melanoma, and each may present differently based on many factors, including skin tone. Many melanomas are flat or barely raised. They may have a variation of colors with irregular borders. The thickness of the melanom  Read More

Melasma is common, harmless and usually fades after a few months. It does not always require treatment. Melasma is produced by hormonal fluctuations, like those that happen during pregnancy or when using birth control pills, and it will diminish after delivery or when the drugs are stopped.A dermatologist will most likely recommend a high-SPF sunblock to avoid melasma.If melasma does not dissipate naturall  Read More

The specific symptoms and severity of syringomyelia can vary greatly from one person to another. Some individuals may not have any noticeable symptoms (asymptomatic); others may have a variety of symptoms that can progress to cause significant disability. It is important to note the highly variable nature of syringomyelia and to realize that affected individuals can have different sets of symptoms and a different rate of progression (or no pro  Read More

The onset of Mucha-Habermann disease is usually sudden and is marked by the development of a recurrent rash consisting of rounded, elevated lesions (papules or macules) that may be itchy and burning. These lesions are usually reddish-purple to reddish-brown and may progress to develop a blackish-brown crust, tissue death (necrosis) and bleeding (hemorrhaging). The lesions eventually blister, often causing scarring or temporary discoloration up  Read More

Neonatal lupus is a rare autoimmune disorder that is present at birth (congenital). Affected infants often develop a characteristic red rash or skin eruption. In addition, infants with neonatal lupus may develop liver disease, a heart condition known as congenital heart block, and/or low numbers of circulating blood platelets that assist in blood clotting functions (thrombocytopenia). The symptoms associated with neonatal lupus, with the excep  Read More

Nodular Nonsuppurative Panniculitis is a rare skin disorder. It is also known as Weber-Christian disease (WCD) or Idiopathic lobular panniculitis.Nodular Nonsuppurative Panniculitis affects men and women of all ages, and mostly it affects adult women. There are fewer chances of nodular nonsuppurative panniculitis affecting children.The nodules are approx 1-2 centimeters large in size. These mostly affect t  Read More

Non-scarring epidermolysis bullosa is a disease that results from mutations in KRT5 or KRT14 gene. These genes provide instructions for making a protein called keratin 5 and 14. There are two major types, and seventeen minor subtypes for this disease, all of which have common effects and symptoms.Among these, the four major subtypes of EBS are here:EBS-loc- in this, blisters are rarely present at birth and ma  Read More

Nonthrombocytopenic idiopathic purpura is a generally self-limited and inflammatory disease of small blood vessels.In mild conditions, no treatment requires just regular monitoring and platelet checking needed, and without treatment, it improves in children, but in some cases, it takes long-term treatment.In that case, some medications are required and some surgeries are also required.Some medicat  Read More

Oculocutaneous albinism is a group of conditions that affect the pigmentation of the skin, hair, and eyes. Affected individuals typically have very fair skin and white or light-colored hair.Long-term sun exposure greatly increases the risk of skin damage and skin cancers, including an aggressive form of skin cancer called melanoma, in people with this condition.Oculocutaneous albinism also reduces pigmenta  Read More

Physical urticaria, cholinergic type or chronic hives is a condition caused by allergen or any substance, body develop allergic reaction. the welts often start as itchy patches that turn into swollen welts that vary in size. These welts appear and fade at random as the reaction runs its course.Chronic hives can be very uncomfortable and interfere with sleep and daily activities.Risk factors-Allerg  Read More

A pilonidal cyst is an abnormal pocket in the skin that usually contains hair and skin debris. A pilonidal cyst is almost always located near the tailbone at the top of the cleft of the buttocks.Pilonidal cysts usually occur when hair punctures the skin and then becomes embedded. If a pilonidal cyst becomes infected, the resulting abscess is often extremely painful.Risk factorsPilonidal cysts most  Read More

Langerhans cell histiocytosis (LCH) is a spectrum of rare disorders characterized by overproduction (proliferation) and accumulation of a specific type of white blood cell (histiocyte) in the various tissues and organs of the body (lesions). The lesions may include certain distinctive Langerhans cells involved in certain immune responses, as well as other white blood cells (e.g.,lymphocytes, monocytes, eosinophils). Associated symptoms and fin  Read More

A hereditary genetic abnormality known as Riley-Day syndrome affects the neurological system of the human body.Dysautonomia, or injury to the autonomic nervous system, results in abnormalities in the autonomic nervous system, which links the brain and spinal cord to the muscles and produces autonomic dysfunction.The body might lose the ability to detect touch, smell, and pain as a result of certain disorde  Read More

Ritter’s Disease is a type of skin infection caused by a bacteria named Staphylococcus aureus. This infection leads to the production of a toxin that can affect skin all over the body. The majority of the time skin gets damaged and sheds.It is uncommon to have Ritter’s Disease. One individual may contract the Staph bacteria that causes Ritter’s Disease from another (contagious).However, a  Read More

Rothmund-Thomson syndrome (RTS) is a rare genetic disorder that can affect many parts of the body. The disorder is characterized by distinctive abnormalities of the skin, sparse hair, eyelashes and/or eyebrows, small stature, skeletal and dental abnormalities, and an increased risk of cancer, especially bone cancer (osteosarcoma). Patients typically begin having signs of RTS during infancy, and the first feature to appear is a rash that starts  Read More

Rothmund-Thomson syndrome is a rare genetic disorder that manifests in early infancy. The range and severity of symptoms may vary from case to case. RTS is typically characterized by skin rash, sparse hair, malformed bones, abnormal clouding of the lenses of the eyes (juvenile cataracts), small stature, and other physical abnormalities. Intelligence is usually normal, but some affected individuals have been reported to have intellectual disabi  Read More

Scabies is an itchy, highly contagious skin disease caused by an infestation by the itch mite Sarcoptes scabiei. Direct skin-to-skin contact is the mode of transmission. A severe and relentless itch is the predominant symptom of scabies. Sexual contact is the most common form of transmission among sexually active young people, and scabies has been considered by many to be a sexually transmitted disease (STD),  Read More

Bloom syndrome is a rare genetic disorder characterized by short stature; increased sensitivity to light (photosensitivity); multiple small dilated blood vessels on the face (facial telangiectasia), often resembling a butterfly in shape; immune deficiency leading to increased susceptibility to infections; and, perhaps most Importantly, a markedly increased susceptibility to cancer of any organ, but especially to leukemia and lymphoma. Some cli  Read More

An uncommon skin condition, that causes fever and painful rashes due to boosted production of blood cells is known as Sweet Syndrome.It can be caused due to risks during pregnancy, the reaction of some medicines, and other common factors like age, sex, cancer, and health issues.Diagnosis:The Sweet Syndrome detects via two methods:Blood Test: Presence of WBCs and blood disordersSkin  Read More

PXE results in a variety of signs and symptoms that vary in their number, type, and severity from person to person. Certain effects of PXE can cause serious medical problems, while others have less impact. Effects may include: skin changes, changes in the retina of the eye that may result in significant loss of central vision, changes in the cardiovascular system that may involve calcification of arteries and decreased blood flow in the arms a  Read More

Transient Acantholytic Dermatosis (TAD) is also named Grover's disease. It is a rare transient skin disorder. It appears as small, firm, raised red lesions on the skin of the chest and back. It is a temporary skin disease. The red spots that appear are very itchy.Middle-aged men, i.e. men over 50 years of age are mostly affected by this disorder. How transient acantholytic dermatosis is caused is yet not known.  Read More

Trichorhinophalangeal syndrome type ii is also known as Langer-Giedion syndrome. This is a very rare inherited disorder. This disorder affects multisystem parts of the body. It may result in thin hair, dystrophic nails, and small breasts.Some skeletal-related findings are short stature, short feet, radial deviation of the fingers, and marked hip dysplasia.Characterized by multiple osteochondromas and moder  Read More

UROD deficiency means a Lack of the enzyme uroporphyrinogen decarboxylase (UROD), which is a basic cause of porphyria cutanea tarda (PCT).This is a type of porphyria in which affected individuals are sensitive to sunlight. PCT is caused by a deficiency of UROD enzymes in the liver.There are three types of PCT that can be classified as type-1, type-2, and type-3.To cure these conditions, sunlight a  Read More

Physical urticaria is a subtype of urticaria that is caused by an extrinsic physical stimulus rather than occurring naturally. There are 7 subcategories of diseases that are classified as distinct diseases. Physical urticaria is considered to be unpleasant, itchy, and physically repulsive; it can last for months or years.Physical urticaria has no established aetiology, but it has been proposed that it is an autoimm  Read More

An uncommon congenital skin condition known as Van Lohuizen Syndrome, is marked by discoloured patches of skin (livedo reticularis) brought on by dilated surface blood vessels (telangiectases), which give the skin a ""fishnet"" or blue or purple appearance. This condition is commonly accompanied by skin sores (Ulcers) that resemble craters. At least 50% of those with the condition also have other congenital  Read More

Vitiligo has no known cure. The purpose of medical therapy is to achieve a consistent skin tone by restoring colour (repigmentation) or removing the remaining colour (depigmentation).SurgerySkin grafts obtained from the patient: Skin is taken from one portion of the patient and utilised to cover another. Scarring, infection, and inability to repigment are all possible problems. it can also be called mic  Read More

Vitiligo Capitis is a condition that results in patchy loss of skin pigment. With time, the discoloured spots typically enlarge. Any portion of the body's skin might be impacted by the illness. The tongue and hair can both be impacted by it.Treatment or Cure available for the Vitiligo Capitis conditionThe type of treatment you receive will depend on your age, the location and amount of skin affected  Read More

Von Zumbusch Disease is characterized by cutaneous lesions, inflammation, and tissue damage (necrosis) of blood vessel walls (lumen).Before beginning treatment, it's crucial to ascertain whether there is an underlying condition that contributes to the Von Zumbusch Disease.The term "vasculitides" or "vasculitic syndromes" refers to a larger class of diseases that affect blood vessels  Read More

Wells' syndrome, also named eosinophilic cellulitis, is a skin disease that is very rare. There occur rashes on the skin that are so painful that the touch may feel burning, raised, red, or swollen on the skin.The person affected by this skin condition may be because of bites from spiders, fleas, bees, mites, or ticks, i.e., arthropods.But the actual and exact cause is not yet known.The sympto  Read More

White Darier disease is also named as Keratosis Follicularis.It is a very rare skin disorder and is genetic.It is characterized by lesions on the skin that have thickened, rough bumps i.e., papules that appear greasy, yellow or skin color or brown crust.These lesions may spread and grow over time. This may vary from person to person. This mostly affects scalp, forehead, upper arms, chest, back, kn  Read More

Wiskott Aldrich syndrome is a syndrome that contains various conditions resulting from a mutation in WAS gene. Mutation in WAS gene results in a deficiency in WASP protein then platelet count starts decreasing. That is called thrombocytopenia. This disease is of immunological deficiency and reduced ability to form blood clots.In this disease, the problems like bloody diarrhea, recurrent infections, scaling, itchy s  Read More

Waardenburg syndrome (WS) is a group of genetic disorders named after Dutch ophthalmologist and geneticist Petrus Johannes Waardenburg, who described it. This is an autosomal dominant inherited disorder. This rare disease results in the loss of pigmentary cells in the eyes, skin, stria vascularis of the cochlea, and hair.This type of disease may cause features like facial abnormalities like the diminished coloratio  Read More