Acantholysis bullosa is a genetic disease, which means that it is caused by one or more genes not working correctly.Risk factors-Acantholysis bullosa is a genetic condition that is usually rare. This condition makes skin so weak that it can tear or blister at the slightest touch. Children born with it are often called "Butterfly Children" because their skin is very fragile, just like butterfly wings.  Read More

Acanthosis bullosa is a painful condition charecterised by large painful blisters on the skin of f patient. this condition tends to make the skin very weak similar to a butterfly. the patients will have blisters even on simple skin rubbing or other conditions. Even tiny wounds caused by heat, rubbing, scraping, or adhesive tape may result in blisters. Blisters may develop inside the body in extreme circumstances, such as on the stomach or the lin  Read More

Acanthosis Nigricans is a condition characterized by discoloration and dark patches in the armpits, neck creases, and other regions. It usually has a velvety black appearance. Though it does not have any medical issue, it affects the aesthetic appearance of the person. It is commonly associated with obesity, diabetes, and other lifestyle conditions. Sometimes it is also seen along with a cancerous condition.Acantho  Read More

Seborrheic Keratosis is a skin disorder usually characterized by discolored lesions that appear to be "stuck on" the skin surface. Warts may appear and skin is often oily or greasy. These skin lesions are sometimes mistaken for cancerous growths and tend to appear predominately during middle age. Itching, irritation, inflammations or unsightliness of lesions may require surgical removal of affected skin areas.  Read More

Acne is a skin condition that occurs when your hair follicles become plugged with oil and dead skin cells. It often causes whiteheads, blackheads or pimples, and usually appears on the face, forehead, chest, upper back and shoulders. Acne is most common among teenagers, though it affects people of all ages. Effective treatments are available, but acne can be persistent. The pimples and bumps heal slowly, and when one begins to go away,  Read More

Acne (acne vulgaris, common acne) is a disease of the hair follicles of the face, chest, and back that affects almost all teenagers during puberty -- the only exception being members of a few primitive Neolithic tribes living in isolation. It is not caused by bacteria, although bacteria play a role in its development. It is not unusual for some women to develop acne in their mid- to late-20s. Acne appears on the skin as...  Read More

An actinic keratosis (ak-TIN-ik ker-uh-TOE-sis) is a rough, scaly patch on your skin that develops from years of exposure to the sun. It's most commonly found on your face, lips, ears, back of your hands, forearms, scalp or neck. Also known as a solar keratosis, an actinic keratosis enlarges slowly and usually causes no signs or symptoms other than a patch or small spot on your skin. These patches take years to develop, usually first a  Read More

Argyria is a rare condition that causes the skin to turn blue or grey. This discolouration happens when the body comes into contact with excessive amounts of silver.There is no defined treatment for this disease. It can be treated by the restriction of the underlying cause.This could be the use of colloidal silver therapy, hydroquinone usage for skin conditions, silver dental fillings etc.When the  Read More

The term albinism typically refers to oculocutaneous (ok-u-low-ku-TAY-nee-us) albinism (OCA) — a group of inherited disorders where there is little or no production of the pigment melanin. The type and amount of melanin your body produces determines the color of your skin, hair and eyes. Melanin also plays a role in the development of optic nerves, so people with albinism have vision problems. Signs of albinism are usually appare  Read More

Chikungunya is a rare viral infection transmitted by the bite of an infected mosquito. It is characterized by a rash, fever, and severe joint pain (arthralgias) that usually lasts for three to seven days. Because of its effect on the joints, Chikungunya has been classified among the Arthritic Viruses. It primarily occurs in tropical areas of the world.  Read More

Atopic dermatitis facts Atopic dermatitis is a type of eczema. The disease may be inherited and genetically determined. The patient's skin may be "super sensitive" to many irritants. Dry, scaly patches develop in a characteristic distribution. Itching varies but may be intense and scratching hard to resist. Scratching can cause skin thickening and darkening and lead to further co  Read More

The symptoms of Frey syndrome typically develop within the first year after surgery in the area near the parotid glands. In some cases, Frey syndrome may not develop until several years after surgery. The characteristic symptom of Frey syndrome is gustatory sweating, which is excessive sweating on the cheek, forehead, and around the ears shortly after eating certain foods, specifically foods that produce a strong salivary response such as sour  Read More

Black tongue, in most cases, resolves by regularly brushing your tongue with a toothbrush.Medications:Your doctor may also prescribe a topical retinoid medication to help increase cell turnover on your tongue.For stubborn elongated papillae, a doctor can remove them using carbon dioxide laser burning or electrodesiccation, which simultaneously cuts and seals the papillae.Cure throu  Read More

Bloom syndrome is a rare genetic disorder characterized by short stature; increased sensitivity to light (photosensitivity); multiple small dilated blood vessels on the face (facial telangiectasia), often resembling a butterfly in shape; immune deficiency leading to increased susceptibility to infections; and, perhaps most Importantly, a markedly increased susceptibility to cancer of any organ, but especially to leukemia and lymphoma. Some cli  Read More

Bloom syndrome is a rare genetic disorder characterized by short stature; increased sensitivity to light (photosensitivity); multiple small dilated blood vessels on the face (facial telangiectasia), often resembling a butterfly in shape; immune deficiency leading to increased susceptibility to infections; and, perhaps most Importantly, a markedly increased susceptibility to cancer of any organ, but especially to leukemia and lymphoma. Some cli  Read More

Blue rubber bleb nevus syndrome is also known as Bean syndrome. It is a rare syndrome of venous malformations that arise in the skin and gastrointestinal tract.Risk factors.Since the disease is a genetic disorder, there are no risk factors associated with this disease. However, consanguineous marriage is a leading cause of disease transmission.Some patients may have mutations in genetic levels, which can affect  Read More

Boils (skin abscesses) if they are small, can generally be treated at home by applying warm compresses to relieve pain and promote natural drainage. In severe cases, medications and further treatment may be needed.Apply warm compresses and heated water to a boil. In addition to bringing the pus to the surface, this will lessen the pain.When the boil reaches its peak, repeated soaks will cause it to rupture  Read More

Branchio-oculo-facial syndrome (BOFS) is a very rare genetic disorder that is apparent at birth (congenital). As of 2004, only about 50 cases of BOFS had been reported in the medical literature. The symptoms of most BOFS patients include the proliferation of blood vessels (hemangiomatous) in the lower neck or upper chest, low birth weight, retarded growth and some mental retardation. BOFS is characterized by the presence of a pseudocleft of th  Read More

Bullous pemphigoid is a rare skin condition that causes large, fluid-filled blisters. They develop on areas of skin that often flex - such as the lower abdomen, upper thighs or armpits. Bullous pemphigoid is most common in older adults.TreatmentFor moderate-to-severe cases of bullous pemphigoid, your healthcare provider may prescribe an oral corticosteroid, like prednisone in addition to a steroid-spari  Read More

Carate, also known as Pinta, is a skin disease caused by a spiral-shaped bacterium called Treponema Carateum.The signs and symptoms of Carate are as follows:Carate only affects the skin. It begins as itchy, flat, reddened areas on the arms, hands, face, feet, legs, or neck.These affected areas enlarge and thicken; however, after several months, some three to nine months later, further thickened  Read More

  Cellulitis is a spreading bacterial infection of the skin and tissues beneath the skin. Staphylococcus and Streptococcus are the types of bacteria that are usually responsible for cellulitis, although many types of bacteria can cause the condition. Sometimes cellulitis appears in areas where the skin has broken open, such as the skin near ulcers or surgical wounds. Symptoms and signs include  Read More

Chanarin Dorfman syndrome is a rare hereditary disorder of fat (lipid) metabolism. It is characterized by scaly skin (ichthyosis), degeneration of the muscles (myopathy), and abnormal white blood cells with small spaces (vacuoles) filled with fat (lipids).  Read More

Symptoms of classic CHS include: brown or light-colored hair with a silvery sheen light colored eyes white or grayish skin tone nystagmus (involuntary eye movements) frequent infections in the lungs, skin, and mucous membranes Other symptoms that infants or young children with CHS may experience are: poor vision photoph  Read More

Symptoms of classic CHS include: brown or light-colored hair with a silvery sheen light colored eyes white or grayish skin tone nystagmus (involuntary eye movements) frequent infections in the lungs, skin, and mucous membranes Other symptoms that infants or young children with CHS may experience are: poor vision photoph  Read More

Chickenpox infection appears 10 to 21 days after exposure to the virus and usually lasts about five to 10 days. The rash is the telltale indication of chickenpox. Other signs and symptoms, which may appear one to two days before the rash, include: Fever Loss of appetite Headache Tiredness and a general feeling of being unwell (malaise) Once the chickenpox rash appears, it goes throug  Read More

Chilblains (CHILL-blayns) are the painful inflammation of small blood vessels in your skin that occur in response to repeated exposure to cold but not freezing air. Also known as pernio, chilblains can cause itching, red patches, swelling and blistering on your hands and feet. Chilblains usually clear up within one to three weeks, especially if the weather gets warmer. You may have recurrences seasonally for years. Treatment involves p  Read More

Congenital or Child Naevus (moles) generally don't cause problems unless they show cancerous signs.Cure/medications include:Your child's doctor will need to check the mole over time to watch for any changes that may signal a future risk of skin cancer.On the other hand, if you worry about the mole's appearance or location, you can talk to your doctor about removal.Discussing with the d  Read More

Contact dermatitis usually occurs on areas of your body that have been directly exposed to the reaction-causing substance — for example, along a calf that brushed against poison ivy or under a watchband. The rash usually develops within minutes to hours of exposure and can last two to four weeks. Signs and symptoms of contact dermatitis include: A red rash Itching, which may be severe Dry, crack  Read More

Oculocerebral Syndrome with Hypopigmentation is an extremely rare inherited disorder characterized by the lack of normal color (hypopigmentation) of the skin and hair and abnormalities of the central nervous system that affect the eyes and certain parts of the brain (oculocerebral). Physical findings at birth include unusually light skin color and silvery-gray hair. Abnormal findings associated with the central nervous system may include abnor  Read More

Gianotti-Crosti syndrome (GCS), papular acrodermatitis of childhood or acrodermatitis is a rare, childhood skin condition that affects children between the ages of 3 months and 15 years.Gianotti-Crosti syndrome is characterized by a papular rash with blisters on the skin of the legs, buttocks, and arms.Skin lesions typically last at least 10 days but may last for several weeks. GCS is a response to the und  Read More

Cutis laxa is rarely encountered and may occur in several inherited (congenital) forms or come about in the course of another disorder (acquired). It is a connective tissue disorder characterized by skin that is loose (lax), hanging, wrinkled, and lacking in elasticity (hyperelasticity). The affected areas of skin may be thickened and dark. In addition, the joints are loose (hypermobility) because of lax ligaments and tendons. The disorder inv  Read More

De Barsy syndrome is a rare, autosomal recessive genetic disorder, the main characteristics of which are a prematurely aged-looking face (progeria), cloudy corneas, short stature, and mental retardation. The condition is expressed in variable presentations involving complicated patterns of ocular, facial, skeletal, dermatologic and neurological abnormalities.  Read More

Cysts are non-cancerous abnormal growth that causes pain and swelling. A person may develop various kinds of cysts anywhere in the body. However, it is curable.The treatment and cure of the cyst:The procedure of removing the cyst depends on the type, size, and area in which it occurred. For instance, if the cyst is really large, the medical expert will perform surgery on it.Sometimes, the docto  Read More

Keratosis follicularis, also known as Darier disease, is a rare, genetic skin disorder. Affected individuals develop skin lesions that consist of thickened, rough bumps (papules) or plaques that may also be greasy or have a brown or yellow crust. These hardened, scaly lesions are progressive and may gradually grow bigger or spread. The nails and mucous membranes are also affected in most cases. Individuals may have periods of time when signs i  Read More

Keratosis follicularis, also known as Darier disease, is a rare, genetic skin disorder. Affected individuals develop skin lesions that consist of thickened, rough bumps (papules) or plaques that may also be greasy or have a brown or yellow crust. These hardened, scaly lesions are progressive and may gradually grow bigger or spread. The nails and mucous membranes are also affected in most cases. Individuals may have periods of time when signs i  Read More

De Barsy syndrome is a rare, autosomal recessive genetic disorder, the main characteristics of which are a prematurely aged-looking face (progeria), cloudy corneas, short stature, and mental retardation. The condition is expressed in variable presentations involving complicated patterns of ocular, facial, skeletal, dermatologic and neurological abnormalities.  Read More

De Barsy syndrome is a rare, autosomal recessive genetic disorder, the main characteristics of which are a prematurely aged-looking face (progeria), cloudy corneas, short stature, and mental retardation. The condition is expressed in variable presentations involving complicated patterns of ocular, facial, skeletal, dermatologic and neurological abnormalities.  Read More

De Sanctis-Cacchione syndrome is an extremely rare disorder characterized by the skin and eye symptoms of xeroderma pigmentosum (XP) occurring in association with neurological abnormalities, mental retardation, unusually short stature (dwarfism), and underdevelopment of the testes or ovaries (hypogonadism). Xeroderma pigmentosum is a group of rare inherited skin disorders characterized by a heightened reaction to ultraviolet light (photosensit  Read More

Deciduous skin is defined as the periodic, continuous, or seasonal peeling or shedding of the epidermal skin layer considering a generalized distribution.Deciduous skin is also referred to as the peeling skin syndrome (PSS), which is a rare autosomal recessive form of ichthyosis.This is clinically characterized by asymptomatic, superficial, and spontaneous peeling of the skin.It is also histologic  Read More

Degos disease is an extremely rare disorder in which small and medium sized arteries become blocked (occlusive arteriopathy), restricting the flow of blood to affected areas. Degos disease usually causes characteristic skin lesions that may last for a period of time ranging from weeks to years. In some individuals, Degos disease will be limited to the skin (benign cutaneous Degos disease); other individuals will also develop symptoms affecting  Read More

Ulcers in and near the mouth due to the infectious organism are called Dichuchwa (Bejel) Disease. It caused the transmission of the organism in a body through infected food utensils.Incidence:It occurs during the teenage and adolescent ages like:55% are from 16 years and above.20% involves people of adult ages.25% percent of children of six years and above found till date.  Read More

Sjogren-Larsson syndrome is an inherited disorder characterized by scaling skin (ichthyosis), mental retardation, speech abnormalities, and spasticity. Affected infants develop various degrees of reddened skin with fine scales soon after birth. After infancy, the skin loses its redness and dark scales often appear on the neck and under the arms. Additionally, larger plate-like thick scales may develop on the lower legs. Developmental delay, sp  Read More

CHILD syndrome is usually present at birth. It may first become apparent at some point during the first month of life. The skin is usually dry, itchy, red and scaly (ichthyosiform erythroderma) on one side of the body, although minor skin involvement in the shape of lines or segments may occur on the opposite side of the body. Bands of normal skin may be found on the affected side as well. Patients with CHILD syndrome may be bald on on  Read More

Harlequin ichthyosis is a rare genetic skin disorder. The newborn infant is covered with plates of thick skin that crack and split apart. The thick plates can pull at and distort facial features and can restrict breathing and eating. Harlequin infants need to be cared for in the neonatal intensive care unit immediately. Harlequin ichthyosis is inherited as an autosomal recessive trait.  Read More

Ichthyosis hystrix, Curth-Macklin type is characterized by patches of abnormally thick, hard skin that may appear almost anywhere on the body. Some clinicians describe the skin as “horn-like”. With treatment, the patches may be considerably reduced. Under examination by electron microscopy, numerous cells (keratinocytes) with two nuclei are found. Frequently, the nuclei are surrounded by shells of a primitive, precursor protein of  Read More

Chanarin-Dorfman syndrome can affect many systems. All patients have skin findings that are usually present at birth: redness, fine scaling, dark pigmentation and severe itching which leads to scratching and skin-picking (excoriation). The skin appearance is referred to “ichthyosiform nonbullous erythroderma”. Patients also have liver disease with lipid storage which can lead to liver failure. About 60% of patients also have muscle  Read More

Dry skin is often temporary — you get it only in winter, for example — but it may be a lifelong condition. Signs and symptoms of dry skin depend on your age, your health, where you live, time spent outdoors and the cause of the problem. Dry skin is likely to cause one or more of the following: A feeling of skin tightness, especially after showering, bathing or swimming Skin that feels and looks rough  Read More

DH is one of the itchiest rashes possible. Common locations of the rash include: elbows knees lower back hairline back of the neck shoulders buttocks scalp The rash is usually the same size and shape on both sides of the body and often comes and goes. Before a full outbreak of the rash, you may feel the skin in a rash-prone area burn or  Read More

Dupuytren's contracture typically progresses slowly, over years. The condition usually begins as a thickening of the skin on the palm of your hand. As it progresses, the skin on your palm might appear puckered or dimpled. A firm lump of tissue can form on your palm. This lump might be sensitive to the touch but usually isn't painful. In later stages of Dupuytren's contracture, cords of tissue form under the skin on your palm and can ex  Read More

Dyskeratosis congenita is a rare genetic form of bone marrow failure, the inability of the marrow to produce sufficient blood cells. Dyskeratosis is Latin and means the irreversible degeneration of skin tissue, and congenita means inborn. First described in the medical literature in 1906, dyskeratosis congenita was originally thought to be a skin disease that also affects the nails and the mouth. Only later in the sixties was it realized that  Read More

There is currently no cure for dyshidrotic eczema; however, treatments can help a person manage this condition. Consulting a dermatologist is necessary to proceed with treatments.Medical treatments for dyshidrotic eczema include:Possible treatments could consist of moisturizing cream or lotion to assist in treating dry skin.Use steroid cream and calcineurin creams to reduce inflammation and les  Read More

Keratosis follicularis, also known as Darier disease, is a rare, genetic skin disorder. Affected individuals develop skin lesions that consist of thickened, rough bumps (papules) or plaques that may also be greasy or have a brown or yellow crust. These hardened, scaly lesions are progressive and may gradually grow bigger or spread. The nails and mucous membranes are also affected in most cases. Individuals may have periods of time when signs i  Read More

E-d syndrome is known as Ehlers- Danlos syndrome, EDS, or elastic skin. This is a type of disorder that mainly affects connective tissue. It is basically a genetic disorder.E-d syndrome is a dominant or recessive genetic condition.E-d syndrome occurs when only a single copy of an abnormal gene is inherited from either parent or can be the result of a new mutation (gene change) in the affected individual.  Read More

Rapp-Hodgkin syndrome, an extremely rare inherited multisystem disorder that is apparent at birth (congenital) or during infancy, belongs to a group of diseases known as ectodermal dysplasias. Ectodermal dysplasias typically affect the skin, teeth, hair, and/or nails. Rapp-Hodgkin syndrome is characterized by a reduced ability to sweat (hypohidrosis); an incomplete closure of the roof of the mouth (cleft palate) and/or an abnormal groove in th  Read More

Johanson-Blizzard syndrome (JBS) is an extremely rare genetic disorder that affects multiple organ systems of the body. Many symptoms are present at birth (congenital) or early childhood. The spectrum of potential features and physical findings associated with JBS is wide and varied and can differ dramatically from one person to another. However, characteristic features include insufficient intestinal absorption (malabsorption) of fats and oth  Read More

Atopic dermatitis or eczema may last for years. To control it, you might need to try a variety of medications over the course of months or years. Additionally, even after successful therapy, signs and symptoms could come back (flare).Early diagnosis of the illness is crucial in order to begin treatment. Your doctor might advise one or more of the following therapies if routine moisturizing and other self-care pract  Read More

Ehlers- Danlos syndrome, EDS, or elastic skin, is a type of disorder that mainly affects connective tissue. It is basically a genetic disorder.E-d syndrome is a dominant or recessive genetic condition.E-d syndrome occurs when only a single copy of an abnormal gene is inherited from either parent or can be the result of a new mutation (gene change) in the affected individual.There are 50% chance of  Read More

The symptoms and progression of pinta may vary among affected individuals. Pinta usually progresses in three separate stages: an early phase with initial lesions; an intermediate phase with widespread (disseminated) lesions; and a late phase. The incubation period may range from seven to 21 days. The skin is the only organ involved in pinta. In most cases, the initial lesions (primary) are small, reddish (erythematous) spots (papules)  Read More

Epidermal nevus syndromes (ENSs) are a group of rare complex disorders characterized by the presence of skin lesions known as epidermal nevi associated with additional extra-cutaneous abnormalities, most often affecting the brain, eye and skeletal systems. Epidermal nevi are overgrowths of structures and tissue of the epidermis, the outermost layer of the skin. The different types of epidermal nevi can vary in size, number, location, distribut  Read More

If lifestyle adjustments and personal care do not manage the symptoms and signs of epidermolysis bullosa, medicines, surgery, and rehabilitation may be used. Despite therapy, the illness frequently worsens, resulting in major complications and death.Medications:Medications can help manage pain and itching, as well as address problems including bloodstream infection (sepsis). If the wounds show evidence  Read More

Epidermolysis bullosa acquisita is an uncommon autoimmune blistering disorder characterized by tight subepithelial blisters at trauma sites. Epidermolysis bullosa acquisita, unlike Epidermolysis bullosa, is not hereditary and usually manifests in adulthood.Epidermolysis bullosa acquisita blisters are typically found in vulnerable locations like the hands, feet, elbows, knees, and buttocks. Mucosal involvement occas  Read More

An accurate diagnosis is crucial to properly inform and counsel parents about epidermolytic hyperkeratosis or epidermolytic ichthyosis (EI). Prenatal diagnosis and genetic counseling are other options.Infection, secondary sepsis, and electrolyte imbalance are all heightened risks for newborns with epidermolytic ichthyosis who have denuded skin. The neonatal ICU should receive these infants so that it can monitor th  Read More

Cells that have Epiloia cease dividing when they ought to. This means that many parts of your body can develop tumours. While they are not cancerous, the areas where they are growing may experience issues. There are Treatments available that can reduce the tumours and increase your comfort.Cure or medications for EpiloiaIn case of seizures, anti-seizure medications may be prescribed. Other medications m  Read More

The erythema multiforme rash The EM rash can consist of dozens of target-shaped (bull’s-eye pattern) lesions that develop over a 24-hour period. These lesions can start on the backs of hands and tops of feet before spreading to the trunk. They may also develop on the face and neck. The arms may be more affected than the legs. These lesions can be concentrated  Read More

Erythema Multiforme Bullosum can range from mild to severe. The skin rash caused by erythema multiforme minor is typically caused by a modest disease. Mucous membranes may be severely affected by erythema multiforme major, which can be severe mucous membranes, and usually requires more intensive therapy.Risk factors for erythema multiforme bullosumThese are the risk factors involved to Erythema Multifor  Read More

Until recently the relationship of Stevens-Johnson syndrome to other severe blistering disorders was a matter of some debate. Now a consensus seems to be evolving that describes SJS as a rare disorder involving lesions of the mucous membranes along with small blisters on the reddish or purplish, flat, thickened patches of skin. As a result, SJS is now distinguished as a separate disorder from erythema multiforme major (EMM). SJS is now conside  Read More

The main symptom is red, painful bumps on the lower part of your legs. Sometimes these bumps can also appear on your thighs, arms, torso, and face. The lumps can be one-half inch up to 4 inches. You may have anywhere from two to 50 of them. Erythema nodosum bumps are painful and they may feel hot. They start out red, and then turn purple, looking like bruises as they heal. They also flatten out while healing. The bumps  Read More

An abnormal increase in RBC and disbalance in hemoglobin flow in blood results in skin rashes, Clotting, and an enlarged spleen; these disorders are called Erythremia.This disease can affect the lungs and blood circulatory system severely if the symptoms are left ignored and not treated immediately.Causes/risk factors:It is a common rash disease that can increase due to skin friction, acne, and po  Read More

KWE is characterized by the cyclical patchy redness and thickening of the skin of the palms and soles, followed by the appearance dry blisters which subsequently peel in an expanding pattern. The shedding skin has a thickish peel. The revealed surface skin appears glazed. These signs first appear during infancy or childhood and the disorder usually improves with age. The condition may be worsened by cold weather or episodes of fever. Secondary  Read More

Erythropoietic protoporphyria (EPP) is a rare inherited metabolic disorder characterized by a deficiency of the enzyme ferrochelatase (FECH). Due to abnormally low levels of this enzyme, excessive amounts of protoporphyrin accumulate in the bone marrow, blood plasma, and red blood cells. The major symptom of this disorder is hypersensitivity of the skin to sunlight and some types of artificial light, such as fluorescent lights (photosensitivit  Read More

The coordinated efforts of a group of experts may be necessary for the treatment of mixed cryoglobulinemia. It may be necessary for pediatricians, dermatologists, neurologists, nephrologists, hepatologists, specialists in the diagnosis and treatment of blood problems (hematologists), and other medical professionals to systematically and thoroughly organize a patient's care.The primary goal of treatment is to addres  Read More

Type 1 Classic Phenotype The signs and symptoms of males with the type 1 classic phenotype typically begin in childhood or adolescence (Desnick 2001, Desnick and Brady 2004). Symptoms increase with age primarily due to the progressive glycolipid accumulation in the micro-vascular system, kidney podocytes, and cardiomyocytes leading to kidney insufficiency and failure, heart disease, and/or strokes. Early and progressive clinical sympto  Read More

Peeling skin syndrome is a rare inherited skin disorder characterized by painless, continual, spontaneous skin peeling (exfoliation). Other findings may include blistering and/or reddening of the skin (erythema) and itching (pruritus). Peeling skin syndrome may clinically overlap with Netherton syndrome, which is also an autosomal recessive skin disorder belonging to the group of congenital ichthyoses, with onset in the neonatal period and inf  Read More

Skin peeling syndrome or familial continuous skin peeling happens on its own, is painless, and can last a lifetime while gradually getting better. Like skin peeling after a severe sunburn, affected people and/or their caretakers might frequently manually remove sheets of skin.Applying skin-softening (emollient) ointments to treat peeling skin syndrome, particularly after a bath when the skin is moist, may provide s  Read More

FDH is a rare disorder that primarily affects females and has extreme variability. It is characterized by skin lesions that look streaked, underdeveloped or “punched-out”, birth defects of the hands and feet and birth defects of the eyes. There may be inflammation, itching, reddening, blistering, and crusting of the skin. Skin may be absent, discolored or lack color (pigmentation) in some areas. The nails may be absent or appear ab  Read More

FDH is a rare disorder that primarily affects females and has extreme variability. It is characterized by skin lesions that look streaked, underdeveloped or “punched-out”, birth defects of the hands and feet and birth defects of the eyes. There may be inflammation, itching, reddening, blistering, and crusting of the skin. Skin may be absent, discolored or lack color (pigmentation) in some areas. The nails may be absent or appear ab  Read More

Formaldehyde Poisoning is a disorder brought about by breathing the fumes of formaldehyde. This can occur while working directly with formaldehyde, or using equipment cleaned with formaldehyde. Major symptoms may include eye, nose, and throat irritation; headaches; and/or skin rashes.  Read More

Formaldehyde Poisoning is a disorder brought about by breathing the fumes of formaldehyde. This can occur while working directly with formaldehyde, or using equipment cleaned with formaldehyde. Major symptoms may include eye, nose, and throat irritation; headaches; and/or skin rashes.  Read More

Fox-Fordyce disease is a rare skin disorder that primarily affects women. The disorder is characterized by intense itching especially in the underarm area, the pubic area and around the nipples. In Fox-Fordyce disease abnormalities affecting the apocrine sweat glands causes inflammation, and enlargement of the glands and the characteristic intense itching. Skin near an affected area may become darkened and dry and multiple, small, raised bumps  Read More

Freckles, commonly known as Ephelides are seen as diffused discolouration or tanning in some parts of the face and the body. However, there are some genetic predispositions to this condition. It cannot be caused by genetic factors alone. Sun exposure is one of the important factors in acquiring this condition.Over-the-counter treatmentPeople with freckles can go for over-the-counter products like AHA to  Read More

The severe form of the disease is called typical mucolipidosis IV, and the mild form is called atypical mucolipidosis IV. Approximately 95 percent of individuals diagnosed with this condition have the severe form. The symptoms and physical findings associated with mucolipidosis IV are usually apparent within three to eight months following birth. The first recognized symptoms are usually clouding (opacity) of the cornea and eye movemen  Read More

Damaged tissue from gangrene cannot be saved. However, medication is available to help avoid gangrene from worsening. The sooner you receive therapy, the greater your chances of recovery.Gangrene treatment may comprise one or more of the following: Medication: Antibiotics are administered intravenously or orally to treat bacterial infections. To alleviate discomfort, pain medicines may be admini  Read More

Gianotti-Crosti Syndrome is characterized by blisters on the skin that may or may not itch. They are usually found on the face, buttocks, arms or legs. The blisters consist of large, flat-topped, fluid filled sacks. They usually occur along with upper respiratory tract infection. The blisters usually last from twenty to twenty-five days; they do not usually recur. There may be an enlargement of the lymph nodes in the trunk area of the body. Gi  Read More

The symptoms of PSEK usually develop shortly after birth or during the first year of life. Infants develop reddened plaques of thickened, rough and/or scaly skin, especially on the face, buttocks, arms and legs. Over time, these lesions can cover large areas of the body. The distribution of these lesions is almost perfectly symmetrical, meaning the size, shape and location of the lesions are extremely similar on both sides of the body. These p  Read More

Fabry disease is a rare genetic disorder of fat (lipid) metabolism characterized by a deficiency of the enzyme alpha-galactosidase A (previously known as ceramide trihexosidase). The disorder belongs to a group of diseases known as lysosomal storage disorders. Lysosomes function as the primary digestive units within cells. Enzymes within lysosomes break down or digest particular compounds and intracellular structures. Alpha-galactosidase funct  Read More

Chronic granulomatous disease (CGD) is a rare inherited primary immune deficiency disorder that affects certain white blood corpuscles (neutrophils, monocytes, macrophages, eosinophils). The disorder is characterized by an inability to resist repeated infectious diseases and a tendency to develop chronic inflammation. Life-threatening recurrent fungal and bacterial infections affecting the skin, lungs, and bones may occur along with swollen ar  Read More

Grover’s disease can usually be treated using topical medications, but sometimes requires oral medication, injections, or light therapy to treat it.Cortisone cream: Your dermatologist will prescribe you a cortisone cream if you have a small blister or outbreak that doesn’t itch.Tetracycline: If you have larger outbreaks that itch and cover the entire trunk, your dermatologist may prescribe the  Read More

Lichen sclerosus is a chronic skin disorder that most commonly affects post-menopausal women. However, it is sometimes identified among pre-menopausal women, and, even more rarely, among males. When found in males, the disease is known as balanitis xerotica obliterans. Lichen sclerosus is characterized by skin changes of the external genitalia (i.e., vulva, head of the penis), although other parts of the body may also be affected.  Read More

Lichen Planus is a rare, recurrent, itchy rash or area of inflammatory eruptions (lesions) of unknown origin characterized by shiny reddish-purple spots on the skin and gray-white ones in the mouth. The disorder may present as itchy spots on the wrist, legs, torso, genitals, mouth, or lips. The eruptions may appear as small separate, angular spots that may coalesce into rough scaly patches. This disorder is frequently accompanied by oral lesio  Read More

Lichen sclerosus is a chronic skin disorder that most commonly affects post-menopausal women. However, it is sometimes identified among pre-menopausal women, and, even more rarely, among males. When found in males, the disease is known as balanitis xerotica obliterans. Lichen sclerosus is characterized by skin changes of the external genitalia (i.e., vulva, head of the penis), although other parts of the body may also be affected.  Read More

Gottron syndrome (GS) is an extremely rare inherited disorder characterized by the appearance of premature aging (progeria), especially in the form of unusually fragile, thin skin on the hands and feet (distal extremities). GS is described as a mild, nonprogressive, congenital form of skin atrophy due to the loss of the fatty tissue directly under the skin (subcutaneous atrophy). Other findings may include abnormally small hands and feet with  Read More

Hallermann-Streiff syndrome (HSS) is a rare genetic disorder that is primarily characterized by distinctive malformations of the skull and facial (craniofacial) region; sparse hair (hypotrichosis); eye abnormalities; dental defects; degenerative skin changes (atrophy), particularly in the scalp and nasal regions; and proportionate short stature. Characteristic craniofacial features include a short, broad head (brachycephaly) with an unusually  Read More

Hallermann-Streiff syndrome (HSS) is a rare genetic disorder that is primarily characterized by distinctive malformations of the skull and facial (craniofacial) region; sparse hair (hypotrichosis); eye abnormalities; dental defects; degenerative skin changes (atrophy), particularly in the scalp and nasal regions; and proportionate short stature. Characteristic craniofacial features include a short, broad head (brachycephaly) with an unusually  Read More

A genetic skin condition called hallopeau-siemens disease or dystrophic epidermolysis bullosa causes blisters to grow. One of the more severe types is the Hallopeau-Siemens syndrome type.Due to the defect's location in the dermis at the dermo-epidermal junction, even little skin trauma results in profuse blister production that always heals with scars.Anchoring fibrils are either absent or inadequate due t  Read More

Harlequin ichthyosis is a rare genetic skin disorder. The newborn infant is covered with plates of thick skin that crack and split apart. The thick plates can pull at and distort facial features and can restrict breathing and eating. Harlequin infants need to be cared for in the neonatal intensive care unit immediately. Harlequin ichthyosis is inherited as an autosomal recessive trait.  Read More

Harley syndrome or Harlequin syndrome is a rare dysautonomic syndrome caused by the unilateral blockade of the T2-T3 fibers carrying sudomotor and vasomotor supply to the face.The autonomic nervous system is responsible for regulating the natural processes of the body, including sweating, skin flushing, and the response of the pupils to any stimuli. The exact cause of the condition is not found yet.The sym  Read More

Hay-Wells syndrome, also known as ankyloblepharon-ectodermal dysplasia-clefting (AEC) syndrome, is a rare inherited disorder that belongs to a group of disorders known as the ectodermal dysplasias. Major characteristics of Hay-Wells syndrome include sparse, coarse, wiry hair; small, sparse eyelashes; excess bands of fibrous tissue that cause the edges (margins) of the upper and lower eyelids to fuse together (ankyloblepharon filiforme adnatum)  Read More

Heat rash facts Heat rash occurs when the skin's sweat glands are blocked and the sweat produced cannot get to the surface of the skin to evaporate. This causes inflammation that results in a rash. Common symptoms of heat rash include red bumps on the skin, and a prickly or itchy feeling to the skin (also known as prickly heat). The rash appears as reddened skin with tiny blisters and is due to inflammation.  Read More

Usually, hematoma underneath the skin and within soft tissues such as muscles can be treated at home using the following methods:Elastic bandages help to keep swelling at bay.Elevating the affected area to alleviate swellingUsing ice packs multiple times each day for the first 24 to 48 hours to minimize swelling and soreness.Warm compresses after 2 days of ice to aid in the fluid's absorp  Read More

HS is divided into mild, moderate, and severe forms of the disease. Classification is based on the amounts of hemoglobin, reticulocytes, and bilirubin and the amount of spectrin in red blood cells. Hemoglobin transports oxygen in the blood. Reticulocytes are immature red blood cells. Bilirubin is formed in the liver when hemoglobin is broken down. Spectrin is a protein that helps keep the shape of a cell. Decreased hemoglobin and spectrin and  Read More

Hidradenitis axillaris is an inflammatory skin disease that causes painful, pus-filled cysts to form in the sweat glands around the groin, armpits, and breasts, primarily around the hair follicles. It happens when hair follicles become obstructed. This particular skin condition is common from puberty until mid-life. And it disproportionately affects women. The severity and specific symptoms of Hidradenitis axillaris differ bet  Read More

Hidradenitis suppurativa commonly occurs around hair follicles with many oil and sweat glands, such as in the armpits, groin and anal area. It may also occur where skin rubs together, such as the inner thighs, under the breasts and between the buttocks. Hidradenitis suppurativa can affect one spot or multiple areas of the body. Signs and symptoms of hidradenitis suppurativa include: Blackheads. Small pit  Read More

The goal of treatment for Hidrosadenitis suppurativa is to prevent the formation of new lesions and to manage the symptoms of pain and suppuration of current lesions.Treatment is a combination of medications, surgery or both.Combined medical and surgical approaches help manage hidradenitis suppurativa.Surgery is an important part of disease management when a tunnel and abscess are present.  Read More

Papular urticaria, usually called hives, is characterized by large numbers of very itchy red bumps (papules) that come and go every few days over a period of a month or so. The bumps are usually between 0.2 and 2 cm. in size and some may develop into fluid-filled blisters (bullae). This condition is usually triggered by allergic reactions to insect bites, sensitivity to drugs, or other environmental causes. In some cases, swelling of the soft  Read More

Cowpox is a viral disease that normally affects the udders and teats of cows. On rare occasions, it may be transmitted to humans and produce a characteristic red skin rash and abnormally enlarged lymph nodes (lymphadenopathy). Cowpox is caused by the vaccinia virus and has been known to cause systemic reactions (generalized vaccinia) in some people who have been recently vaccinated against cowpox.Cowpox produces immunity to smallpo  Read More

A hereditary skin condition known as epidermolysis ichthyosis (EI) is distinguished by different degrees of blistering and subsequent reactive scaling of the skin. Mid-epidermal splitting and hyperkeratosis, often known as epidermolytic hyperkeratosis, are present in the underlying histology (EHK). The symptoms might range from minor burning upon friction to severe erosions or widespread warty scaling, depending on the kind of  Read More

Ichthyosis is a general term for a family of rare genetic skin diseases characterized by dry, thickened, scaling skin. The various forms are distinguished from one another by: 1) extent of the scaling and how widely and where the scaling is scattered over the body; 2) the presence or absence and intensity of reddening of the skin (erythroderma); 3) the mode of inheritance; and 4) the character of associated abnormalities.  Read More

Ichthyosis Congenita is a type of genetic skin disorder that is very rare. It is also known as Harlequin ichthyosis or Keratosis Diffusa Foetalis. It happens to be in 1 person out of 3,00,000 births worldwide.This condition occurs in the child if either of the parents has this. If both the genes are defective, then the chances of birth of a child with ichthyosis congenita are in very severe form.There appe  Read More

KWE is characterized by the cyclical patchy redness and thickening of the skin of the palms and soles, followed by the appearance dry blisters which subsequently peel in an expanding pattern. The shedding skin has a thickish peel. The revealed surface skin appears glazed. These signs first appear during infancy or childhood and the disorder usually improves with age. The condition may be worsened by cold weather or episodes of fever. Secondary  Read More

Harlequin ichthyosis is a rare genetic skin disorder. The newborn infant is covered with plates of thick skin that crack and split apart. The thick plates can pull at and distort facial features and can restrict breathing and eating. Harlequin infants need to be cared for in the neonatal intensive care unit immediately. Harlequin ichthyosis is inherited as an autosomal recessive trait.  Read More

Harlequin ichthyosis is a rare genetic skin disorder. The newborn infant is covered with plates of thick skin that crack and split apart. The thick plates can pull at and distort facial features and can restrict breathing and eating. Harlequin infants need to be cared for in the neonatal intensive care unit immediately. Harlequin ichthyosis is inherited as an autosomal recessive trait.  Read More

Ichthyosis hystrix, Curth-Macklin type is characterized by patches of abnormally thick, hard skin that may appear almost anywhere on the body. Some clinicians describe the skin as “horn-like”. With treatment, the patches may be considerably reduced. Under examination by electron microscopy, numerous cells (keratinocytes) with two nuclei are found. Frequently, the nuclei are surrounded by shells of a primitive, precursor protein of  Read More

Ichthyosis hystrix, Curth-Macklin type is characterized by patches of abnormally thick, hard skin that may appear almost anywhere on the body. Some clinicians describe the skin as “horn-like”. With treatment, the patches may be considerably reduced. Under examination by electron microscopy, numerous cells (keratinocytes) with two nuclei are found. Frequently, the nuclei are surrounded by shells of a primitive, precursor protein of  Read More

Keratosis follicularis spinulosa decalvans (KFSD) is a rare, inherited, skin disorder that affects men predominately and is characterized by hardening of the skin (keratosis) in several parts of the body. Most frequently, the face, neck, and forearms are involved. The thickening of the skin is accompanied by the loss of eyebrows, eyelashes and beard. Baldness (alopecia) usually occurs.  Read More

A rare inherited skin condition known as ichthyosis lamellar manifests at the birth of a child.Ichthyosis lamellar is one of the three autosomal recessive congenital ichthyoses, which are inherited skin conditions (ARCI). The other two are referred to as congenital ichthyosiform erythroderma and harlequin ichthyosis.The clinical spectrum is the term used to describe all ARCI conditions. The symptoms of sev  Read More

Netherton syndrome is a rare hereditary disorder characterized by scaling skin, hair anomalies, increased susceptibility to atopic eczema (a skin condition that can result in dry, red and flaky skin), elevated IgE levels, and other related symptoms. Netherton syndrome is inherited as an autosomal recessive trait.  Read More

Sjogren-Larsson syndrome is an inherited disorder characterized by scaling skin (ichthyosis), mental retardation, speech abnormalities, and spasticity. Affected infants develop various degrees of reddened skin with fine scales soon after birth. After infancy, the skin loses its redness and dark scales often appear on the neck and under the arms. Additionally, larger plate-like thick scales may develop on the lower legs. Developmental delay, sp  Read More

Ichthyosis Vulgaris is caused by an inherited genetic flaw, a mutation that affects a large protein called filaggrin.The faulty gene is inherited from one's parents and may be caused by one or more mutations in the profillagrin gene that occur early in fetal development.It is autosomal dominant, which means that all that is required for the condition is a single faulty copy of the gene that codes for f  Read More

A genetic disorder due to chromosomal disbalance or mutation that result in scaly and flaky skin in male is called Ichthyosis X Linked disease.Risk factors:Mutation of the enzyme steroid sulfatase is responsible for the foremost cause of the disease Ichthyosis X Linked.Deficiency of the enzyme steroid sulfate halts the metabolism of cholesterol sulfate.•It leads to cholesterol s  Read More

Chanarin-Dorfman syndrome can affect many systems. All patients have skin findings that are usually present at birth: redness, fine scaling, dark pigmentation and severe itching which leads to scratching and skin-picking (excoriation). The skin appearance is referred to “ichthyosiform nonbullous erythroderma”. Patients also have liver disease with lipid storage which can lead to liver failure. About 60% of patients also have muscle  Read More

Mild immune thrombocytopenia/idiopathic thrombocytopenic purpura (ITP) patients might only require routine monitoring and platelet tests. Children typically get better on their own. Most individuals with ITP will require therapy at some point, as the condition frequently gets worse or is chronic (chronic).Numerous methods of treatment are possible, such as taking drugs to increase your platelet count or having your  Read More

Impetigo is a commonly transmitted skin infection. Bacteria such as Staphylococcus aureus and Streptococcus pyogenes infect the epidermis, or outer layers of the skin. The face, arms, and legs are the most commonly affected areas.Impetigo can affect anyone, although it is more frequent in children, particularly those aged 2 to 5.Minor cuts, bug bites, or a rash like eczema — any spot where the skin is damaged  Read More

Specific treatment for incontinentia pigmenti has not yet been described. However, the management of the disease requires a multidisciplinary approach and needs consultation with different specialists from time to time.Lesions appear within a few months from birth but disappear by adolescence. However, the lesions recur and require to be managed.All stage lesions must be kept cool and dry.The patients develop hypo  Read More

Each patient's unique symptoms are targeted in the treatment of Infantile Myofibromatosis (IM).Surgery is the primary treatment for people with infantile myofibromatosis, and it is carried either to lessen the risk of complications or increase prognosis.The coordinated efforts of a group of professionals may be necessary throughout treatment.To arrange a child's treatment, pediatricians, o  Read More

Apnea is a term used to describe the temporary absence of spontaneous breathing. Infantile apnea occurs in children under the age of one year. Apnea may occur because of neurological impairment of the respiratory rhythm or obstruction of air flow through the air passages. The symptoms of infantile apnea include the stoppage of breathing during sleep, an abnormal bluish discoloration to the skin (cyanosis) and sometimes an unusually slow heartb  Read More

Intertrigo is a dermatitis that only affects skin folds. Intertrigo is caused when skin is irritated by friction, which is enhanced by moisture and heat. Risk factors for intertrigo include obesity, heat, and humidity. Intertrigo patients complain of redness, burning, and itching in the skin folds. Occasionally, long-standing intertrigo may produce a musty smell. Intertrigo is diagnosed by visual in  Read More

Hypomelanosis of Ito is a rare condition characterized by distinctive skin changes, in which areas of the body lack skin color (hypopigmentation). These skin changes may present as patches, streaks or spiral-shaped (whorled) areas. In many cases, additional symptoms affecting areas outside of the skin also occur. There are a wide variety of symptoms potentially associated with hypomelanosis of Ito. Neurological findings such as seizures and de  Read More

Patients living with lymphocytic infiltrate of Jessner may experience symptoms including itchiness (pruritus), redness of the skin (erythema), and pimple-like eruptions (papules), most commonly on areas exposed to sunlight. These pimple-like lesions may last up to several months. As they extend from the perimeter, these lesions form well-defined, smooth, red patches (plaques) whose diameter may go as far as up to one inch. Occasionally  Read More

Jock itch usually begins with a reddened area of skin that spreads out from the crease in the groin in a half-moon shape onto the upper thigh. The border of the rash may consist of a line of small, raised blisters. The rash often itches or burns, and the skin may be flaky or scaly. When to see a doctor See your doctor if you have a rash on your skin that doesn't improve within two weeks or if you treat it with over-the-counte  Read More

Johnson –stevens disease is a very rare syndrome with potentially fatal skin reactions in which loss of skin occurs and mucosal membranes accompanied by systemic symptoms is shown in some case. For these conditions, in 80% of cases, the reactions from medications are responsible.This condition requires intensive care or burn care unit in hospitalization,If a person is taking unessential medication  Read More

Kabuki syndrome is a rare, multisystem disorder characterized by multiple abnormalities including distinctive facial features, growth delays, varying degrees of intellectual disability, skeletal abnormalities, and short stature. A wide variety of additional symptoms affecting multiple different organ systems can potentially occur. The specific symptoms associated with Kabuki syndrome can vary greatly from one person to another. The exact cause  Read More

The following are keloids treatments. One or more ways may be appropriate for your scenario. Keloids can grow back, sometimes larger than before, even after effective flattening or excision. You might also create new ones.Wound healing: Compression dressings composed of elastic cloth or other materials may be used as the first treatment choice for newer keloids. This treatment is frequently used to remove keloids a  Read More

Keratitis ichthyosis deafness (KID) syndrome is a rare, genetic, multi-system disorder. It is characterized by defects of the surface of the corneas (keratitis), red, rough thickened plaques of skin (erythrokeratoderma) and sensorineural deafness or severe hearing impairment. The skin on the palms of the hands and soles of the feet and the nails may be affected. KID syndrome belongs to a group of skin disorders marked by dry, scaly skin known  Read More

Pitted keratolysis is a skin illness that develops microscopic holes in your skin's top layer.It primarily affects the soles of your feet, but it can also affect your hands' palms.This condition's little holes or pits usually do not pain or itch, but they might become tender or irritating.They may also experience a burning feeling.These bacteria multiply at infection sites and  Read More

KWE is characterized by the cyclical patchy redness and thickening of the skin of the palms and soles, followed by the appearance dry blisters which subsequently peel in an expanding pattern. The shedding skin has a thickish peel. The revealed surface skin appears glazed. These signs first appear during infancy or childhood and the disorder usually improves with age. The condition may be worsened by cold weather or episodes of fever. Secondary  Read More

Keratosis follicularis is a genetic condition that emerges at random as a consequence of a sudden genetic alteration or as an autosomal dominant feature.Genetic disorders are caused by the combination of genes for a specific trait on the chromosomes inherited from both parents.Dominant genetic illnesses develop when only one copy of a defective gene is required for the disease to manifest.The faul  Read More

Haim-Munk syndrome is a rare genetic disorder characterized by the development of red, scaly thickened patches of skin on the palms of the hands and soles of the feet (palmoplantar hyperkeratosis), frequent pus-producing (pyogenic) skin infections, overgrowth (hypertrophy) of the fingernails and toenails (onychogryposis), and degeneration of the structures that surround and support the teeth (periodontosis). Periodontosis usually results in th  Read More

Keratosis Pilaris (KP), or chicken skin, is a skin disorder that appears as small bumps on the skin and is usually mistaken as goosebumps or small pimples.Keratin, i.e. proteins produced by the skin in large quantities, blocks hair follicles, and this leads to the development of red bumps on the skin.None can define why keratin is built up in keratosis pilaris. Itchiness and irritation can be felt on the s  Read More

Seborrheic Keratosis is a skin disorder usually characterized by discolored lesions that appear to be "stuck on" the skin surface. Warts may appear and skin is often oily or greasy. These skin lesions are sometimes mistaken for cancerous growths and tend to appear predominately during middle age. Itching, irritation, inflammations or unsightliness of lesions may require surgical removal of affected skin areas.  Read More

The Koebner disease or phenomenon affects persons who have specific skin conditions, most often psoriasis. It can occur in persons who have warts, vitiligo, or lichen planus. An accident, cut, or burn might result in new lesions that seem similar to the initial skin illness.There is no known treatment for the Koebner phenomena.Treatment is usually the same because the phenomenon is essentially an extens  Read More

Lamellar ichthyosis is a condition that mainly affects the skin. Infants with this condition are typically born with a tight, clear sheath covering their skin called a collodion membrane.Risk factors-Infants with lamellar ichthyosis may develop infections, an excessive loss of fluids (dehydration), and respiratory problems.Mutations in the TGM1 gene are responsible for approximately 90 percent  Read More

The condition lamellar ichthyosis type 1 and type 2 mostly affects the skin. A collodion membrane, which is a tight, transparent sheath covering the skin, is frequently seen on newborns with this disorder.During the first few weeks of life, this membrane typically dries and peels off, making the affected babies' scaly skin, outward-curling eyes, and lips evident.The majority of the body is often covere  Read More

If you're allergic to latex, you're likely to have symptoms after touching latex rubber products, such as gloves or balloons. You can also have symptoms if you breathe in latex particles that are released into the air when someone removes latex gloves. Latex allergy symptoms range from mild to severe. A reaction depends on how sensitive you are to latex and the amount of latex you touch or inhale. Your reaction can become worse with ea  Read More

Madelung’s disease is characterized by the presence of fatty tumors (lipomas) located symmetrically around the neck, shoulders, trunk, hips, upper arms and thighs. While these abnormal fatty tumors may grow over the course of months to years, the disease usually demonstrates a rapid progression at first and then slows down as the size of the fatty mass stabilizes. The rest of the body may be lean in contrast to the affected parts.  Read More

Granuloma annulare is a chronic degenerative skin disorder. The most common form is localized granuloma annulare, which is characterized by the presence of small, firm red or yellow colored bumps (nodules or papules) that appear arranged in a ring on the skin. In most cases, the sizes of the lesions range from one to five centimeters. The most commonly affected sites include the feet, hands, and fingers. In addition to the localized form, ther  Read More

Lichen planus facts Lichen planus is a chronic recurrent rash of unknown cause with no established cure. Lichen planus generally affects adults and can involve any portion of the body, but it has a predilection for the wrists, ankles, and oral and genital tissues. Lichen planus can be quite itchy. Lichen planus may spontaneously resolve. Lichen planus is managed with a variety of topical a  Read More

Lichen Planus is a rare, recurrent, itchy rash or area of inflammatory eruptions (lesions) of unknown origin characterized by shiny reddish-purple spots on the skin and gray-white ones in the mouth. The disorder may present as itchy spots on the wrist, legs, torso, genitals, mouth, or lips. The eruptions may appear as small separate, angular spots that may coalesce into rough scaly patches. This disorder is frequently accompanied by oral lesio  Read More

A rare, chronic skin ailment called Lichen Psoriasis causes small patches of skin to thin down and turn colourless. Any region of the body can be affected, although the skin around the genitals is most frequently affected. Men and children can occasionally develop Lichen Psoriasis, although most occurrences afflict women who have undergone menopause.The proper medical care can manage Lichen Psoriasis. Here are the  Read More

Lichen Planus is a rare, recurrent, itchy rash or area of inflammatory eruptions (lesions) of unknown origin characterized by shiny reddish-purple spots on the skin and gray-white ones in the mouth. The disorder may present as itchy spots on the wrist, legs, torso, genitals, mouth, or lips. The eruptions may appear as small separate, angular spots that may coalesce into rough scaly patches. This disorder is frequently accompanied by oral lesio  Read More

Sometimes, mild cases of lichen sclerosus cause no noticeable signs or symptoms. When they do occur, lichen sclerosus symptoms may include: Itching (pruritus), which can be severe Discomfort or pain Smooth white spots on your skin Blotchy, wrinkled patches Easy bruising or tearing In severe cases, bleeding, blistering or ulcerated lesions Painful intercourse  Read More

Lichen sclerosus is a chronic skin disorder that most commonly affects post-menopausal women. However, it is sometimes identified among pre-menopausal women, and, even more rarely, among males. When found in males, the disease is known as balanitis xerotica obliterans. Lichen sclerosus is characterized by skin changes of the external genitalia (i.e., vulva, head of the penis), although other parts of the body may also be affected.  Read More

Papular urticaria, usually called hives, is characterized by large numbers of very itchy red bumps (papules) that come and go every few days over a period of a month or so. The bumps are usually between 0.2 and 2 cm. in size and some may develop into fluid-filled blisters (bullae). This condition is usually triggered by allergic reactions to insect bites, sensitivity to drugs, or other environmental causes. In some cases, swelling of the soft  Read More

Treatment for linear sebaceous nevus sequence is directed toward the specific symptoms that are apparent in each individual.The doctor may wait unless there are obvious deformities that need to be addressed.Pediatricians, neurologists, dermatologists, and other healthcare professionals may need to plan the treatment systematically and comprehensively.Therapeutic procedures and interventions specif  Read More

Lipoma is usually painless and harmful, but if it is bothering you, or growing further, then it needs to be removed.Lipoma treatments include:Surgical removal: Lipomas are mostly removed through surgery by cutting them out. However, there are chances that they may occur again. Since the surgery may leave a scar or get the area bruised, minimal excision extraction may be performed so that it results in l  Read More

Localized Epidermolysis bullosa simplex (EBS) is a genetic disease, which means that it is caused by one or more genes not working correctly.The majority of EBS subtypes are inherited in a dominant manner. This means that an affected parent passes them on to half of his or her offspring. EBS affects both men and women equally.Epidermolysis bullosa simplex is often transmitted in an autosomal dominant manne  Read More

Patients living with lymphocytic infiltrate of Jessner may experience symptoms including itchiness (pruritus), redness of the skin (erythema), and pimple-like eruptions (papules), most commonly on areas exposed to sunlight. These pimple-like lesions may last up to several months. As they extend from the perimeter, these lesions form well-defined, smooth, red patches (plaques) whose diameter may go as far as up to one inch. Occasionally  Read More

Degos disease is an extremely rare disorder in which small and medium sized arteries become blocked (occlusive arteriopathy), restricting the flow of blood to affected areas. Degos disease usually causes characteristic skin lesions that may last for a period of time ranging from weeks to years. In some individuals, Degos disease will be limited to the skin (benign cutaneous Degos disease); other individuals will also develop symptoms affecting  Read More

Melanoma is a type of cancer. It may also be called malignant melanoma or cutaneous melanoma. Most melanomas are brown and black, but they can also be pink, tan, or even white. There are four main types of melanoma, and each may present differently based on many factors, including skin tone. Many melanomas are flat or barely raised. They may have a variation of colors with irregular borders. The thickness of the melanom  Read More

Melasma causes patches of discoloration. The patches are darker than your usual skin color. It typically occurs on the face and is symmetrical, with matching marks on both sides of the face. Other areas of your body that are often exposed to sun can also develop melasma. Brownish colored patches usually appear on the: cheeks forehead bridge of the nose chin It can also occur  Read More

Signs and symptoms of molluscum contagiosum include bumps on the skin that: Are raised, round and flesh colored Are small — typically under about 1/4 inch (smaller than 6 millimeters) in diameter Characteristically have a small indentation (umbilication) or dot at the top near the center Can become red and inflamed May be itchy Can be easily removed by scratching or rubbing  Read More

Morgagni-Stewart-Morel syndrome is in-short, known as MSM syndrome.The exact cause of the disease is yet to be unraveled, and its manifestations are yet to be completely described.The disease was known to cause neurological manifestations.However, endocrinal and metabolic abnormalities have been found to be associated with the disease.The autosomal dominant genetic mutations have been bel  Read More

The specific symptoms and severity of syringomyelia can vary greatly from one person to another. Some individuals may not have any noticeable symptoms (asymptomatic); others may have a variety of symptoms that can progress to cause significant disability. It is important to note the highly variable nature of syringomyelia and to realize that affected individuals can have different sets of symptoms and a different rate of progression (or no pro  Read More

The onset of Mucha-Habermann disease is usually sudden and is marked by the development of a recurrent rash consisting of rounded, elevated lesions (papules or macules) that may be itchy and burning. These lesions are usually reddish-purple to reddish-brown and may progress to develop a blackish-brown crust, tissue death (necrosis) and bleeding (hemorrhaging). The lesions eventually blister, often causing scarring or temporary discoloration up  Read More

Necrotizing fasciitis (flesh-eating disease) progresses rapidly and can result in death hence an early diagnosis and providing appropriate treatment is of utmost importance.Early medical treatment is often presumptive; antibiotics should be started as soon as this condition is suspected.Surgical debridement is the standard treatment for necrotizing fasciitis.Aggressive Necrotizing fasciitis should  Read More

Neonatal jaundice, also named infant jaundice, in mild cases, often disappears on its own within two or three weeks. In severe conditions, your child may need the following treatments.Good nutrition: there are recommendations for frequent feedings and other supplements for nutritionPhototherapy: A spectrum of blue and green light bulbs is placed for a baby; this light changes the shape and structure of bil  Read More

Neonatal lupus is a rare autoimmune disorder that is present at birth (congenital). Affected infants often develop a characteristic red rash or skin eruption. In addition, infants with neonatal lupus may develop liver disease, a heart condition known as congenital heart block, and/or low numbers of circulating blood platelets that assist in blood clotting functions (thrombocytopenia). The symptoms associated with neonatal lupus, with the excep  Read More

Nodular Nonsuppurative Panniculitis is a rare skin disorder. It is also known as Weber-Christian disease (WCD) or Idiopathic lobular panniculitis.Nodular Nonsuppurative Panniculitis affects men and women of all ages, and mostly it affects adult women. There are fewer chances of nodular nonsuppurative panniculitis affecting children.The nodules are approx 1-2 centimeters large in size. These mostly affect t  Read More

Non-scarring epidermolysis bullosa is a disease that results from mutations in KRT5 or KRT14 gene. These genes provide instructions for making a protein called keratin 5 and 14. There are two major types, and seventeen minor subtypes for this disease, all of which have common effects and symptoms.Among these, the four major subtypes of EBS are here:EBS-loc- in this, blisters are rarely present at birth and ma  Read More

Henoch-Schonlein purpura is a rare inflammatory disease of the small blood vessels (capillaries) and is usually a self-limited disease. It is the most common form of childhood vascular inflammation (vasculitis) and results in inflammatory changes in the small blood vessels. The symptoms of Henoch-Schonlein purpura usually begin suddenly and may include headache, fever, loss of appetite, cramping abdominal pain, and joint pain. Red or purple sp  Read More

Alkaptonuria is a rare genetic metabolic disorder characterized by the accumulation of homogentisic acid in the body. Affected individuals lack enough functional levels of an enzyme required to breakdown homogentisic acid. Affected individuals may have dark urine or urine that turns black when exposed to air. However, this change may not occur for several hours after urination and often goes unnoticed. Aside from dark urine that is present fro  Read More

Oculocutaneous albinism (OCA) is a group of rare inherited disorders characterized by a reduced amount or complete lack of melanin pigment in the skin, hair, and eyes. These conditions are caused by mutations in specific genes that are necessary for the production of melanin pigment in specialized cells called melanocytes. Absent or insufficient melanin pigment results abnormal development in the eyes resulting in vision abnormalities and ligh  Read More

KWE is characterized by the cyclical patchy redness and thickening of the skin of the palms and soles, followed by the appearance dry blisters which subsequently peel in an expanding pattern. The shedding skin has a thickish peel. The revealed surface skin appears glazed. These signs first appear during infancy or childhood and the disorder usually improves with age. The condition may be worsened by cold weather or episodes of fever. Secondary  Read More

Idiopathic nodular panniculitis is a rare spectrum of skin disorders characterized by single or multiple, tender or painful bumps below the surface of the skin subcutaneous nodules) that can be open sores and usually lead to inflammation of the subcutaneous layer of fat (panniculitis).These nodules tend to be 1-2 centimeters in size and most often affect the legs and feet Rare cases involve panniculitis of the brea  Read More

Papillon-Lefèvre syndrome is characterized by the development of dry scaly patches of skin (hyperkeratosis) usually around the age of one to five years. These patches are usually confined to the undersides of the hands and feet, but may spread to the knees and elbows. Rarely, the upper portions of the hands and feet, the eyelids, the lips, the cheeks, and/or other areas of the body may also be affected. Affected skin may be unusually re  Read More

Cholinergic urticaria is a relatively common disorder of the immune system characterized by an immediate skin reaction (hypersensitivity) to heat, emotional stress, and/or exercise. Symptoms of the disorder include the appearance of distinctive small skin eruptions (hives) with well-defined borders and pale centers, surrounded by patches of red skin (wheal-and-flare reaction). These red areas are typically intensely itchy (pruritus). Occasiona  Read More

A pilonidal cyst is an abnormal pocket in the skin that usually contains hair and skin debris. A pilonidal cyst is almost always located near the tailbone at the top of the cleft of the buttocks.Pilonidal cysts usually occur when hair punctures the skin and then becomes embedded. If a pilonidal cyst becomes infected, the resulting abscess is often extremely painful.Risk factorsPilonidal cysts most  Read More

Pityriasis rosea is a rash that often begins as an oval spot on the face, chest, abdomen or back. This is called a herald patch and may be up to 4 inches across. The patients suffering from this disease develop smaller spots that sweep out from the middle of the body in a shape that looks like drooping pine-tree branches. The rash can be itchy.usually, the symptoms and the condition settle down on their own without any m  Read More

Precancerous dermatosis is a skin disease marked by scaly or thickened patches on the skin and often caused by prolonged exposure to arsenic.The patches often occur on sun-exposed areas of the skin and in older white men.These patches may become cancerous.There are many types of this cancerous lesion, including Bowen's disease, actinic keratosis, etc.Precancerous skin growths can have  Read More

Pernicious anemia is a rare blood disorder characterized by the inability of the body to properly utilize vitamin B12, which is essential for the development of red blood cells. Most cases result from the lack of the gastric protein known as intrinsic factor, without which vitamin B12 cannot be absorbed. The symptoms of pernicious anemia may include weakness, fatigue, an upset stomach, an abnormally rapid heartbeat (tachycardia), a  Read More

Treatments for psoriasis try to get rid of scales and slow the rapid growth of skin cells. Options include oral or injectable drugs, light therapy, phototherapy, lotions, and ointments (topical therapy).The severity of psoriasis and how responsive it has been to prior therapies and self-care techniques will determine which treatments you utilize. Before you find a strategy that works, you might need to experiment w  Read More

Langerhans cell histiocytosis (LCH) is a spectrum of rare disorders characterized by overproduction (proliferation) and accumulation of a specific type of white blood cell (histiocyte) in the various tissues and organs of the body (lesions). The lesions may include certain distinctive Langerhans cells involved in certain immune responses, as well as other white blood cells (e.g.,lymphocytes, monocytes, eosinophils). Associated symptoms and fin  Read More

Radiation disease doesn’t have any cure, but a few medications and therapy can extract some radiation from the body. People who are exposed to radiation should seek medical attention as soon as possible.The treatments for Radiation disease are as follows:DTPA (diethylenetriamine penaacetic acid): It binds to the radioactive elements present in the body, such as americium, plutonium, and curium. Fu  Read More

Radiation illness doesn’t have any cure, but a few medications and therapy can extract some radiation from the body. People who are exposed to radiation should seek medical attention as soon as possible.The treatments for Radiation illness are as follows:DTPA (diethylenetriamine penaacetic acid): It binds to the radioactive elements present in the body, such as americium, plutonium, and curium. Fu  Read More

The treatment goals for radiation sickness are to prevent further radioactive contamination; treat life-threatening injuries, such as from burns and trauma; reduce symptoms; and manage pain. Decontamination Decontamination is the removal of as much external radioactive particles as possible. Removing clothing and shoes eliminates about 90 percent of external contamination. Gently washing with water and soap removes additional  Read More

Radiation syndrome doesn’t have any cure, but a few medications and therapy can extract some radiation from the body. People who are exposed to radiation should seek medical attention as soon as possible.The treatments for Radiation syndrome are as follows:DTPA (diethylenetriamine penaacetic acid): It binds to the radioactive elements present in the body, such as americium, plutonium, and curium.  Read More

Rapp-Hodgkin syndrome is a rare disease that is caused by a defect in genes. It can cause problems to hair, nails, skin, teeth, and sweat glands. The child may inherit one faulty gene from each parent and resulting in this syndrome.The child with Rapp-Hodgkin syndrome may have opened in the upper lip, skin erosions, fused eyelids, growth problems, hair loss, and other problems associated with appearance. him99999 U  Read More

Wiedemann-Rautenstrauch syndrome (WRS), also known as neonatal progeroid syndrome, is a very rare genetic disorder characterized by an aged appearance at birth (old man look) growth delays before and after birth (prenatal and postnatal growth retardation), and deficiency or absence of the layer of fat under the skin (subcutaneous lipoatrophy). It is anticipated that most individuals with WRS have decreased life expectancy. There are few indivi  Read More

Recessive x-linked ichthyosis is a genetic skin disorder that results in extremely dry skin. Since it is a genetic disorder it is not curable, but the sign and symptoms can be controlled by the following methods.Skin softening cream and location: This disease is accompanied by fine or rhombus adherents' light gray or dark brown scaling on the skin. It can be treated with softening cream. These creams moisturize  Read More

Familial dysautonomia is a rare genetic disorder of the autonomic nervous system (ANS) that primarily affects people of Eastern European Jewish heritage. It is characterized by diminished sensitivity to pain, lack of overflow tearing in the eyes, a decrease in the number of knob-like projections that cover the tongue (fungiform papillae), unusual fluctuations of body temperature, and unstable blood pressure. Symptoms of this disorder are appar  Read More

Ringworm (tinea corporis) is a skin condition caused by a fungal infection, and no ringworm is involved in it. The name comes from the appearance of circular rashes on the skin.Here are simple cures and medications to treat ringworm.Topical antifungal: Over-the-counter antifungal creams kill the fungus and promote healing. Effective antifungal medications include miconazole, clotrimazole, and terbinafin  Read More

Ritter’s Disease is a type of skin infection caused by a bacteria named Staphylococcus aureus. This infection leads to the production of a toxin that can affect skin all over the body. The majority of the time skin gets damaged and sheds.It is uncommon to have Ritter’s Disease. One individual may contract the Staph bacteria that causes Ritter’s Disease from another (contagious).However, a  Read More

Parry-Romberg syndrome is a rare, acquired disorder characterized by slowly progressive shrinkage (atrophy) of the skin and soft tissues of half of the face (hemifacial atrophy). In rare cases, both sides of the face are affected. In some cases, atrophy may also affect the limbs usually on the same side of the body as the facial atrophy. The severity and specific symptoms of Parry-Romberg syndrome are highly variable from one person to another  Read More

Rosacea is a skin disorder that causes flushing or blushing of blood vessels in the face.Sometimes small bumps filled with pus appear on the skin that causing a burning and stinging sensation on the face.The cause of Rosacea is still unknown, but the doctor states that it may be the result of genes, bacteria, mites bites, or blood vessel trouble.A swollen bulb-shaped nose, large pores, broken bloo  Read More

The symptoms and physical findings associated with Rosai-Dorfman disease vary greatly from one person to another depending upon the extent of the disorder and the specific organ systems affected. Some cases may only affect the lymph nodes and may not cause any serious complications. Less often, some cases may affect various organ systems of the body and may potentially cause serious complications. Any organ system of the body may become affect  Read More

Rothmund-Thomson syndrome (RTS) is a rare genetic disorder that can affect many parts of the body. The disorder is characterized by distinctive abnormalities of the skin, sparse hair, eyelashes and/or eyebrows, small stature, skeletal and dental abnormalities, and an increased risk of cancer, especially bone cancer (osteosarcoma). Patients typically begin having signs of RTS during infancy, and the first feature to appear is a rash that starts  Read More

Rothmund-Thomson syndrome is a rare genetic disorder that manifests in early infancy. The range and severity of symptoms may vary from case to case. RTS is typically characterized by skin rash, sparse hair, malformed bones, abnormal clouding of the lenses of the eyes (juvenile cataracts), small stature, and other physical abnormalities. Intelligence is usually normal, but some affected individuals have been reported to have intellectual disabi  Read More

Scabies is an itchy, highly contagious skin disease caused by an infestation by the itch mite Sarcoptes scabiei. Direct skin-to-skin contact is the mode of transmission. A severe and relentless itch is the predominant symptom of scabies. Sexual contact is the most common form of transmission among sexually active young people, and scabies has been considered by many to be a sexually transmitted disease (STD),  Read More

Early signs of SSSS usually begin with the hallmark symptoms of an infection: fever irritability fatigue chills weakness lack of appetite conjunctivitis (an inflammation or infection of the clear lining that covers the white portion of the eyeball) You may also notice the appearance of a crusty sore. The sore typically appears in the diaper region or aro  Read More

Individuals born with Aplasia Cutis Congenita lack skin (and therefore hair), in localized areas of the body, usually, but not always, on the scalp (70 percent of cases). In some cases, the trunk, arms, and/or legs may also be involved. Sometimes, the underlying bone may be missing as well as the skin. The affected area(s) are usually replaced with a thin transparent membrane. In some cases, these affected structures and other organs may be se  Read More

Scalp psoriasis is a form of plaque psoriasis, which causes silvery-red or purplish scaly patches (known as plaques). Plaque psoriasis is the most common psoriasis type. It can affect any part of the body. Scalp psoriasis may also spread to — and cause plaques to appear on — the: hairline forehead back of the neck back of the ears In addition to plaques, scalp pso  Read More

Systemic sclerosis, commonly referred to as scleroderma, is a group of rare disorders that cause the skin to tighten and harden. Additionally, it could affect the digestive system, internal organs, and blood vessels.Scleroderma is frequently labelled as "limited" or "diffuse," which merely describes how much skin is affected. Both forms may involve any other organ or vascular issues. Skin alone  Read More

Commonly found on the face, neck, upper back, and chest, sebaceous cysts are small lump or bump under the skin. If the condition starts to get worse, it is advisable to consult a doctor. Regular checkups are encouraged to keep it from spreading and causing infection.Risk factorsA sebaceous cyst could result in the following: -Unfavorable effects of treatment- There are no permanent effects o  Read More

The doctor examines your skin to determine whether you have seborrheic dermatitis or not, and your skin is sent for biopsy.If the symptoms resemble seborrheic dermatitis, the doctor continues the treatment by prescribing various shampoos, creams, and lotions.You can also try some home remedies before going for shampoos or lotions.If the home remedy does not work, you can take the treatment by visi  Read More

Bloom syndrome is a rare genetic disorder characterized by short stature; increased sensitivity to light (photosensitivity); multiple small dilated blood vessels on the face (facial telangiectasia), often resembling a butterfly in shape; immune deficiency leading to increased susceptibility to infections; and, perhaps most Importantly, a markedly increased susceptibility to cancer of any organ, but especially to leukemia and lymphoma. Some cli  Read More

A common form of skin cancer on the middle and outer layers of skin is Squamous Cell Type. It is caused due to excessive exposure to Ultraviolet radiation, sunlight, or tanning beds or lamps.Cure/medications for Squamous Cell Type skin cancer:Meet the doctors and specialized dermatologists with the following details and information for the best possible treatment:Medical history of family and the  Read More

A genetic disease caused due to mutations mainly caused due to mutation in the TGM5 gene is called Skin Peeling Syndrome.TGM5 enzymes act as a protective barrier for the outermost layer of the skinScarcity in the production of TGM5 enzyme give rise to the separate layer and peeling off.Light peeling or dryness is common in peopleIf it is happening continuously, it is a syndrome and needs  Read More

Skin tags are a skin growth in which a short soft skin hangs out of the body. These skin tags are painless and harmless and may grow on various sections of the body such as the eyelids, neck, chest, back, and stomach. The outer layer of skin tags might be irregular or smooth in appearance. They are frequently raised from the outer layer of the skin. They are typically skin shaded or brownish in color.Skin tags are  Read More

The first symptoms of smallpox usually appear 10 to 14 days after you're infected. During the incubation period of seven to 17 days, you look and feel healthy and can't infect others. Following the incubation period, a sudden onset of flu-like signs and symptoms occurs. These include: Fever Overall discomfort Headache Severe fatigue Severe back pain Vomiting, possibly  Read More

Stretch marks, medically known as striae, are seen as long, narrow, rippled marks that develop due to rapid stretching or shrinking of the skin. They can be red, brown, purple, black or pink in color. These marks can appear on any body part, but they are most common on stomach, upper arms, breasts, thighs, and lower back.Over-the-counter treatmentRetinol and Hyaluronic acid creams: People with stretch m  Read More

An uncommon skin condition, that causes fever and painful rashes due to boosted production of blood cells is known as Sweet Syndrome.It can be caused due to risks during pregnancy, the reaction of some medicines, and other common factors like age, sex, cancer, and health issues.Diagnosis:The Sweet Syndrome detects via two methods:Blood Test: Presence of WBCs and blood disordersSkin  Read More

PXE results in a variety of signs and symptoms that vary in their number, type, and severity from person to person. Certain effects of PXE can cause serious medical problems, while others have less impact. Effects may include: skin changes, changes in the retina of the eye that may result in significant loss of central vision, changes in the cardiovascular system that may involve calcification of arteries and decreased blood flow in the arms a  Read More

Scleroderma is a rare autoimmune connective tissue disorder characterized by abnormal thickening of the skin. Connective tissue is composed of collagen, which supports and binds other body tissues. There are several types of scleroderma. Some types affect certain, specific parts of the body, while other types can affect the whole body and internal organs (systemic). Scleroderma is also known as progressive systemic sclerosis. The exact cause o  Read More

Tinea versicolor signs and symptoms include: Patches of skin discoloration, usually on the back, chest, neck and upper arms, which may appear lighter or darker than usual Mild itching Scaling When to see a doctor See your doctor if: Your skin doesn't improve with self-care measures The fungal infection returns The patches cover large areas of your b  Read More

The condition known as Torular Meningitis, which is caused by the bacterium Mycobacterium tuberculosis, is characterised by inflammation of the membranes (meninges) surrounding the brain or spinal cord. The problem of Torular Meningitis appears gradually. Antibiotics and other medications are typically effective in treating the infection.Cause of the Torular MeningitisA rare complication of Torular Meni  Read More

Transient Acantholytic Dermatosis (TAD) is also named Grover's disease. It is a rare transient skin disorder. It appears as small, firm, raised red lesions on the skin of the chest and back. It is a temporary skin disease. The red spots that appear are very itchy.Middle-aged men, i.e. men over 50 years of age are mostly affected by this disorder. How transient acantholytic dermatosis is caused is yet not known.  Read More

The range and severity of symptoms varies among individuals with trichorhinophalangeal syndrome type II. Affected individuals will not have all of the symptoms listed below. The most common symptoms include fine, thin hair; unusual facial features; short stature; abnormalities of the hands and feet; and/or development of multiple bony growths (exostoses) projecting outward from the surfaces of various bones of the body. Additional characterist  Read More

The symptoms of PCT can vary greatly from one individual to another. Skin abnormalities characterize this disorder. Affected individuals are abnormally susceptible to damage of the skin from sunlight (photosensitivity). Extremely fragile skin that can peel or blister on minimal impact is common. Affected individuals may develop blistering skin lesions on areas of the skin that are frequently exposed to the sun such as the hands and face. These  Read More

If you’re experiencing CU, you may have: wheals (small, raised bumps on the skin) redness around the bumps itching These bumps typically develop within the first six minutes of exercise. Your symptoms may worsen for the next 12 to 25 minutes. Although wheals can appear on your body, they often begin on your chest and neck first. They may then spread out to other areas. These bump  Read More

Papular urticaria usually appears as itchy, red bumps or blisters on top of the skin. Some blisters can appear in clusters on the body. The bumps are usually symmetrically distributed, and each bump is usually between 0.2 and 2 centimeters in size. Papular urticaria can appear on any part of the body. The bumps and blisters can disappear and reappear on the skin. After a blister disappears, it sometimes leaves behind a dark mark on the  Read More

Perstans hemorrhagica urticaria or Urticaria pigmentosa is a rash that most commonly affects children and young adults.It consists of reddish-brown lesions that, when rubbed, might cause hives or blisters.Darier's sign refers to this reaction.Mastocytosis is a kind of urticaria pigmentosa.Mast cells, which are part of your immune system, accumulate during this time. Mastocytosis can a  Read More

The most common symptoms of physical urticaria are itching (pruritus) and hives consisting of red rings around white ridges (wheals). Sensitivity to cold is usually manifested by these eruptions on the skin, itching, and swelling under the skin (angioedema). These symptoms develop most typically after exposure to cold is terminated and during or after swimming or bathing. Contraction of the muscles around the bronchi (bronchospasm) and even hi  Read More

Since vaginitis can be caused by a variety of species and situations, treatment focuses on the specific cause:Vaginosis is caused by bacteriaFor this type of vaginitis, your doctor may prescribe metronidazole tablets (Flagyl) to take or metronidazole gel (MetroGel) to apply to the affected area. Other treatments include clindamycin (Cleocin) cream applied to the vagina, clindamycin tablets taken orally, or c  Read More

An uncommon congenital skin condition known as Van Lohuizen Syndrome, is marked by discoloured patches of skin (livedo reticularis) brought on by dilated surface blood vessels (telangiectases), which give the skin a ""fishnet"" or blue or purple appearance. This condition is commonly accompanied by skin sores (Ulcers) that resemble craters. At least 50% of those with the condition also have other congenital  Read More

Because this condition affects your blood vessels, symptoms might occur in various parts of your body. There’s no single set of symptoms that can definitely indicate you have necrotizing vasculitis. You might notice initial symptoms on your own without a medical test. These include: chills fatigue fever weight loss Other early symptoms are only detectable through a bloo  Read More

Vitiligo has no known cure. The purpose of medical therapy is to achieve a consistent skin tone by restoring colour (repigmentation) or removing the remaining colour (depigmentation).SurgerySkin grafts obtained from the patient: Skin is taken from one portion of the patient and utilised to cover another. Scarring, infection, and inability to repigment are all possible problems. it can also be called mic  Read More

Alopecia areata is a disorder characterized by loss of hair. Sometimes, this means simply a few bare patches on the scalp. In other cases, hair loss is more extensive. Although the exact cause is not known, this is thought to be an autoimmune disorder in which the immune system, the body's own defense system, mistakenly attacks the hair follicles, the tiny structures from which hairs grow. Unpredictable hair loss is the only noticeable symptom  Read More

Lichen sclerosus is a chronic skin disorder that most commonly affects post-menopausal women. However, it is sometimes identified among pre-menopausal women, and, even more rarely, among males. When found in males, the disease is known as balanitis xerotica obliterans. Lichen sclerosus is characterized by skin changes of the external genitalia (i.e., vulva, head of the penis), although other parts of the body may also be affected.  Read More

Vulgaris type Ichthyosis is an inherited skin condition where the surface of your skin develops thick, dry scales from the accumulation of dead skin cells.Vulgaris type Ichthyosis, also known as fish scale disease or fish skin disease, can cause scales to develop from birth, but this is typically when they first do.Since they are easily mistaken for cases of severely dry skin, modest occurrences of Vulgari  Read More

Warts (common warts) is a viral disease that causes benign skin growths on different parts of the body.TreatmentCommon warts do not require treatment as they are resolved on their own after a few weeks or months.There are two main treatments:Salicylic acid: Salicylic acid gradually dissolves the hard scales upon applying it several times a day for over a few weeks. Most salicylic acid soluti  Read More

An unusual inflammatory condition of the body's fatty tissues is called Weber-Christian disease.Idiopathic lobular panniculitis (ILP) and recurrent febrile nodular panniculitis syndrome are other names for Weber-Christian disease.A collection of disorders that affect the deep fat are frequently referred to as Weber-Christian diseases. Reddish, painful nodules are the earliest signs of these illnesses o  Read More

Short stature, an unusually small head (microcephaly), and brain abnormalities that may cause intellectual incapacity are the hallmarks of the rare genetic illness weber-cockayne disease or cockayne Syndrome (CS).Children who have the condition may also experience photosensitivity, peripheral nerve inflammation, breakdown of the myelin sheath that protects nerve fibers, hearing loss, vision problems like cataracts,  Read More

Weil syndrome, a rare infectious disorder, is a severe form of the bacterial infection caused by Leptospira bacteria known as leptospirosis. Weil syndrome is characterized by dysfunction of the kidneys and liver, abnormal enlargement of the liver (hepatomegaly), persistent yellowing of the skin, mucous membranes, and whites of the eyes (jaundice), and/or alterations in consciousness. In most cases, Weil syndrome occurs among individuals who ar  Read More

Wells' syndrome, also named eosinophilic cellulitis, is a skin disease that is very rare. There occur rashes on the skin that are so painful that the touch may feel burning, raised, red, or swollen on the skin.The person affected by this skin condition may be because of bites from spiders, fleas, bees, mites, or ticks, i.e., arthropods.But the actual and exact cause is not yet known.The sympto  Read More

White Darier disease is also named as Keratosis Follicularis.It is a very rare skin disorder and is genetic.It is characterized by lesions on the skin that have thickened, rough bumps i.e., papules that appear greasy, yellow or skin color or brown crust.These lesions may spread and grow over time. This may vary from person to person. This mostly affects scalp, forehead, upper arms, chest, back, kn  Read More

Wiskott Aldrich syndrome is a syndrome that contains various conditions resulting from a mutation in WAS gene. Mutation in WAS gene results in a deficiency in WASP protein then platelet count starts decreasing. That is called thrombocytopenia. This disease is of immunological deficiency and reduced ability to form blood clots.In this disease, the problems like bloody diarrhea, recurrent infections, scaling, itchy s  Read More

Waardenburg syndrome (WS) is a group of genetic disorders named after Dutch ophthalmologist and geneticist Petrus Johannes Waardenburg, who described it. This is an autosomal dominant inherited disorder. This rare disease results in the loss of pigmentary cells in the eyes, skin, stria vascularis of the cochlea, and hair.This type of disease may cause features like facial abnormalities like the diminished coloratio  Read More