Acanthosis nevus syndrome is much more severe than the acanthosis nigricansTreatment course-The treatment of this condition is a combination of cosmetic therapy and surgeries accompanied by the treatment for the underlying cause of the disease. This improves both the appearance and theThe standard therapy for epidermal nevi is surgery or ablative CO2 laser treatment.Topical tretinoin c  Read More

The most common topical prescription medications for acne are:Retinoids and retinoid-like drugs: Drugs that contain retinoic acids or tretinoin are often useful for moderate acne.Antibiotics: These work by killing excess skin bacteria and reducing redness and inflammation. Examples include clindamycin with benzoyl peroxide (Benzaclin, Duac, othersAzelaic acid and salicylic acid: Azelaic acid is a naturally occurri  Read More

Acne (pimples) is a skin condition characterized by lesions and eruptions on the skin's surface, especially on the face, neck, back, etc. Pimple is usually a less severe variety of acne. It occurs in single or small groups, usually treated with mild over-the-counter drugs and home remedies.Retinoids and retinoid-like drugs: Drugs that contain retinoic acids or tretinoin are often useful for moderate acne.A  Read More

An actinic keratosis (ak-TIN-ik ker-uh-TOE-sis) is a rough, scaly patch on your skin that develops from years of exposure to the sun. It's most commonly found on your face, lips, ears, back of your hands, forearms, scalp or neck. Also known as a solar keratosis, an actinic keratosis enlarges slowly and usually causes no signs or symptoms other than a patch or small spot on your skin. These patches take years to develop, usually first a  Read More

Albinism is a rare genetic condition caused by mutations of certain genes that affect the amount of melanin your body produces. Melanin controls the pigmentation (color) of your skin, eyes, and hair.People with albinism have extremely pale skin, eyes, and hair. They are at an increased risk of vision, skin, and social issues; the patients aren't born with the usual amount of melanin pigment.Melanin is a ch  Read More

Atopic dermatitis, commonly called eczema, is a persistent disease; you may need long-standing treatment for these symptoms. The doctor may recommend some home remedies and hygienic practices to sort out the issue.Cure/medications-Topical creams like calcineurin inhibitors such as tacrolimus (Protopic) and pimecrolimus (Elidel) affect your immune system. They are used by people older than age 2 to help  Read More

Auriculotemporal syndrome or the Frey syndrome is a postoperative phenomenon following salivary gland surgery and also in neck dissection, facelift procedures, and trauma that is characterized by excessive sweating and flushing.The previous sympathetic responses of sweating and flushing are now controlled by postganglionic parasympathetic fibers.Mastication, which releases acetylcholine from the parasympat  Read More

Black tongue, in most cases, resolves by regularly brushing your tongue with a toothbrush.Medications:Your doctor may also prescribe a topical retinoid medication to help increase cell turnover on your tongue.For stubborn elongated papillae, a doctor can remove them using carbon dioxide laser burning or electrodesiccation, which simultaneously cuts and seals the papillae.Cure throu  Read More

The most consistent clinical feature of BSyn, seen throughout all stages of life, is poor growth that affects height, weight and head circumference. This growth deficiency begins before birth, and the affected fetus is typically smaller than normal for gestational age. The average birth weight of affected males is 1760 g (range 900-3189 g) and of affected females, 1754 g (range 700-2892 g). Body proportions are nonetheless normal. The average  Read More

The most consistent clinical feature of BSyn, seen throughout all stages of life, is poor growth that affects height, weight and head circumference. This growth deficiency begins before birth, and the affected fetus is typically smaller than normal for gestational age. The average birth weight of affected males is 1760 g (range 900-3189 g) and of affected females, 1754 g (range 700-2892 g). Body proportions are nonetheless normal. The average  Read More

Blue rubber bleb nevus syndrome (BRBNS) is a rare blood vessel (vascular) disorder that affects the skin and internal organs of the body. Multiple distinctive skin lesions are usually characteristic of this disorder and are often present at birth or present during early childhood. Lesions in the gastrointestinal tract frequently become apparent during childhood or early adulthood. The lesions are multifocal venous malformations, resulting from  Read More

Boils (skin abscesses) if they are small, can generally be treated at home by applying warm compresses to relieve pain and promote natural drainage. In severe cases, medications and further treatment may be needed.Apply warm compresses and heated water to a boil. In addition to bringing the pus to the surface, this will lessen the pain.When the boil reaches its peak, repeated soaks will cause it to rupture  Read More

Branchio-oculo-facial syndrome (BOFS) is a very rare genetic disorder that is apparent at birth (congenital). As of 2004, only about 50 cases of BOFS had been reported in the medical literature. The symptoms of most BOFS patients include the proliferation of blood vessels (hemangiomatous) in the lower neck or upper chest, low birth weight, retarded growth and some mental retardation. BOFS is characterized by the presence of a pseudocleft of th  Read More

Bullous pemphigoid is a rare skin condition that causes large, fluid-filled blisters. They develop on areas of skin that often flex - such as the lower abdomen, upper thighs or armpits. Bullous pemphigoid is most common in older adults.TreatmentFor moderate-to-severe cases of bullous pemphigoid, your healthcare provider may prescribe an oral corticosteroid, like prednisone in addition to a steroid-spari  Read More

Chanarin - Dorfman disease doesn't have any effective cure still, it can be managed in the following ways:A low-fat diet for the minimum accumulation of fat in the body. Moreover, it is recommended to get a dietician for the feeding process of your child.Having a low-fat diet, enriched with medium-chain triglycerides, ursodiol (a bile acid), and vitamin E, would decrease the liver size and normalize the li  Read More

Patients with chilblains are generally prescribed OTC medications purchased at a pharmacy. The condition is treated symptomatically using certain medications.During the diagnostic process, your doctor will diagnose or examine your skin condition.Further tests like skin biopsy may be suggested to rule out other causes for your signs and symptoms.The first line of treatment includes measures to keep  Read More

Congenital or Child Naevus (moles) generally don't cause problems unless they show cancerous signs.Cure/medications include:Your child's doctor will need to check the mole over time to watch for any changes that may signal a future risk of skin cancer.On the other hand, if you worry about the mole's appearance or location, you can talk to your doctor about removal.Discussing with the d  Read More

Cross-McKusick-Breen Syndrome, Oculocerebral Syndrome with Hypopigmentation, Cross Syndrome, Depigmentation-Gingival Fibromatosis-Microphthalmia or Kramer Syndrome is an extremely rare inherited disorder characterized by the lack of normal color of the skin and hair.The skin lacks melanin and as a result, is extremely sensitive to exposure to the sun.It is also associated with impaired vision, breathing di  Read More

Cutis laxa encompasses a group of rare disorders that occur in several inherited congenital forms or are acquired at some point during life -acquired cutis laxa. Cutis laxa involves a wide spectrum of symptoms that result from defects in connective tissue found throughout the body - in muscles, joints, skin and other organs.The treatment of Cutis laxa focuses on managing the symptoms and treating other conditions.  Read More

Cutis laxa is an inherited or acquired disorder of the skin, and connective tissue.The inheritance occurs in an autosomal recessive, dominant, or X-linked fashion.The causative mutations are in the genes for the synthesis of elastin and structural proteins of the extracellular matrix.Particularly, cutis laxa growth deficiency syndrome is characterized by growth and developmental delay and skeletal  Read More

Cysts are non-cancerous abnormal growth that causes pain and swelling. A person may develop various kinds of cysts anywhere in the body. However, it is curable.The treatment and cure of the cyst:The procedure of removing the cyst depends on the type, size, and area in which it occurred. For instance, if the cyst is really large, the medical expert will perform surgery on it.Sometimes, the docto  Read More

Keratosis follicularis, also known as Darier disease, is a rare, genetic skin disorder. Affected individuals develop skin lesions that consist of thickened, rough bumps (papules) or plaques that may also be greasy or have a brown or yellow crust. These hardened, scaly lesions are progressive and may gradually grow bigger or spread. The nails and mucous membranes are also affected in most cases. Individuals may have periods of time when signs i  Read More

Keratosis follicularis, also known as Darier disease, is a rare, genetic skin disorder. Affected individuals develop skin lesions that consist of thickened, rough bumps (papules) or plaques that may also be greasy or have a brown or yellow crust. These hardened, scaly lesions are progressive and may gradually grow bigger or spread. The nails and mucous membranes are also affected in most cases. Individuals may have periods of time when signs i  Read More

De barsy syndrome is a rare genetic disorder that affects the skin, eyes, skeletomuscular and nervous system.It is so rare that only 27 cases have been reported worldwide. It is a genetic disorder, and the conditions are very similar to those of cutis laxa syndrome.The disease has multiple other names; De Barsy-Moens-Diercks syndrome, corneal clouding-cutis laxa-mental retardation, and progeroid syndrome o  Read More

De Barsy Moens-Diercks syndrome is a rare genetic disorder that affects the body's connective tissue. It is distinguished by short stature, developmental delays, and lax cutis (saggy skin that lacks elasticity). The syndrome is named after Dr. Georges de Barsy, who described the condition for the first time in 1931. It usually affects men and women equally. The severity and specific symptoms of De Barsy Moens-Diercks syndrome  Read More

De Sanctis-Cacchione syndrome is an extremely rare disorder characterized by the skin and eye symptoms of xeroderma pigmentosum (XP) occurring in association with neurological abnormalities, mental retardation, unusually short stature (dwarfism), and underdevelopment of the testes or ovaries (hypogonadism). Xeroderma pigmentosum is a group of rare inherited skin disorders characterized by a heightened reaction to ultraviolet light (photosensit  Read More

Deciduous skin is defined as the periodic, continuous, or seasonal peeling or shedding of the epidermal skin layer considering a generalized distribution.Deciduous skin is also referred to as the peeling skin syndrome (PSS), which is a rare autosomal recessive form of ichthyosis.This is clinically characterized by asymptomatic, superficial, and spontaneous peeling of the skin.It is also histologic  Read More

Blockage of blood vessels/arteries restricts the flow to the blood vessels of the skin & other organs, which is Degos Syndrome. It defects the small intestine and other abdominal organs lesions (damage to skin and lining of organs) due to undetected causes.Diagnosis:Tests in the case of this syndrome present nothing but everything normal. It is necessary to have a skin biopsy if a doubt arises.Symptoms reveal a  Read More

The sjögren-Larsson syndrome is a condition characterized by dry, scaly skin (ichthyosis); neurological problems; and eye problems. These symptoms are apparent in early childhood and usually do not worsen with age.Risk factors:People with this condition may also have neurological signs and symptoms. Most affected individuals have leukoencephalopathy, which is a change in a type of brain tissue call  Read More

Harlequin syndrome is a rare disorder of the autonomic nervous system. The blockage results in hemifacial discoloration, sharply demarcated at the midline. It is a self resolutive disease.Treatment/ managementThough Harlequin syndrome may not need treatment, in cases where the individual may feel socially embarrassed, contralateral sympathectomy may be considered.In this treatment, the nerve bu  Read More

Ichthyosis hystrix, Curth-Macklin type is a rare autosomal dominant disorder characterized by dark hyperkeratotic plaques and palmoplantar keratoderma over knuckles, knees, and elbows.The causative mutations occur in the gene KRT1. The gene is responsible for the supramolecular assembly of keratin intermediate filaments.The histological examination of skin lesion biopsies diagnoses the disease through the  Read More

The exceedingly rare genetic ailment Chanarin-Dorfman syndrome (CDS) is characterized by dry, scaly skin at birth, increasing fatty liver disease, and varying degrees of muscle involvement. This syndrome is also accompanied by hearing loss, small stature, vision issues, and slight intellectual handicap.The disease is frequently discovered a few years later in childhood when more symptoms start to appear, even thoug  Read More

Dry skin is often temporary — you get it only in winter, for example — but it may be a lifelong condition. Signs and symptoms of dry skin depend on your age, your health, where you live, time spent outdoors and the cause of the problem. Dry skin is likely to cause one or more of the following: A feeling of skin tightness, especially after showering, bathing or swimming Skin that feels and looks rough  Read More

Dupuytren's contracture is a benign disease whose etiology is similar to that of Peyronie disease, Ledderhose disease, and Garrod disease. It predominantly affects the palmar part of the hands. The disease initiates with nodules along the longitudinal lines of tension.Treatment /managementTreatment options consist conservative management, needle aponeurotomy, collagenase injection, or surgical resection  Read More

Keratosis follicularis, also known as Darier disease, is a rare, genetic skin disorder. Affected individuals develop skin lesions that consist of thickened, rough bumps (papules) or plaques that may also be greasy or have a brown or yellow crust. These hardened, scaly lesions are progressive and may gradually grow bigger or spread. The nails and mucous membranes are also affected in most cases. Individuals may have periods of time when signs i  Read More

E-d syndrome is known as Ehlers- Danlos syndrome, EDS, or elastic skin. This is a type of disorder that mainly affects connective tissue. It is basically a genetic disorder.E-d syndrome is a dominant or recessive genetic condition.E-d syndrome occurs when only a single copy of an abnormal gene is inherited from either parent or can be the result of a new mutation (gene change) in the affected individual.  Read More

Johanson-Blizzard syndrome (JBS) is an extremely rare genetic disorder that affects multiple organ systems of the body. Many symptoms are present at birth (congenital) or early childhood. The spectrum of potential features and physical findings associated with JBS is wide and varied and can differ dramatically from one person to another. However, characteristic features include insufficient intestinal absorption (malabsorption) of fats and oth  Read More

Ehlers- Danlos syndrome, EDS, or elastic skin, is a type of disorder that mainly affects connective tissue. It is basically a genetic disorder.E-d syndrome is a dominant or recessive genetic condition.E-d syndrome occurs when only a single copy of an abnormal gene is inherited from either parent or can be the result of a new mutation (gene change) in the affected individual.There are 50% chance of  Read More

Epidermal nevus syndromes (ENSs) are a group of rare complex disorders characterized by the presence of skin lesions known as epidermal nevi associated with additional extra-cutaneous abnormalities, most often affecting the brain, eye and skeletal systems. Epidermal nevi are overgrowths of structures and tissue of the epidermis, the outermost layer of the skin. The different types of epidermal nevi can vary in size, number, location, distribut  Read More

If lifestyle adjustments and personal care do not manage the symptoms and signs of epidermolysis bullosa, medicines, surgery, and rehabilitation may be used. Despite therapy, the illness frequently worsens, resulting in major complications and death.Medications:Medications can help manage pain and itching, as well as address problems including bloodstream infection (sepsis). If the wounds show evidence  Read More

Cells that have Epiloia cease dividing when they ought to. This means that many parts of your body can develop tumours. While they are not cancerous, the areas where they are growing may experience issues. There are Treatments available that can reduce the tumours and increase your comfort.Cure or medications for EpiloiaIn case of seizures, anti-seizure medications may be prescribed. Other medications m  Read More

The main symptom is red, painful bumps on the lower part of your legs. Sometimes these bumps can also appear on your thighs, arms, torso, and face. The lumps can be one-half inch up to 4 inches. You may have anywhere from two to 50 of them. Erythema nodosum bumps are painful and they may feel hot. They start out red, and then turn purple, looking like bruises as they heal. They also flatten out while healing. The bumps  Read More

Erythrokeratolysis hiemalis is a rare disease associated with palms and soles. When you get affected by this disease, the skin of your palms and soles gets peeled. Itching and postulation happen if someone is affected by this disease. In most cases, the condition is present at the time of birth. But there is also a record of getting the disease during childhood or in adolescent period life.Risk Factors of erythroke  Read More

Type 1 Classic Phenotype The signs and symptoms of males with the type 1 classic phenotype typically begin in childhood or adolescence (Desnick 2001, Desnick and Brady 2004). Symptoms increase with age primarily due to the progressive glycolipid accumulation in the micro-vascular system, kidney podocytes, and cardiomyocytes leading to kidney insufficiency and failure, heart disease, and/or strokes. Early and progressive clinical sympto  Read More

Skin peeling syndrome or familial continuous skin peeling happens on its own, is painless, and can last a lifetime while gradually getting better. Like skin peeling after a severe sunburn, affected people and/or their caretakers might frequently manually remove sheets of skin.Applying skin-softening (emollient) ointments to treat peeling skin syndrome, particularly after a bath when the skin is moist, may provide s  Read More

Formaldehyde Poisoning is a disorder brought about by breathing the fumes of formaldehyde. This can occur while working directly with formaldehyde, or using equipment cleaned with formaldehyde. Major symptoms may include eye, nose, and throat irritation; headaches; and/or skin rashes.  Read More

Formaldehyde Poisoning is a disorder brought about by breathing the fumes of formaldehyde. This can occur while working directly with formaldehyde, or using equipment cleaned with formaldehyde. Major symptoms may include eye, nose, and throat irritation; headaches; and/or skin rashes.  Read More

A skin condition that occurs in sweat-producing areas is known as Fox Fordyce Disease. It is a rare condition that mainly occurs in women between the age of 13 to 35 years. Areas affected by the disease have itchy bumps produced around the hair follicles of the underarm, nipples, and other pubic regions.The ratio of women to men with the disease is more due to sweat accumulation and bacterial production. It is due  Read More

Freckles, commonly known as Ephelides are seen as diffused discolouration or tanning in some parts of the face and the body. However, there are some genetic predispositions to this condition. It cannot be caused by genetic factors alone. Sun exposure is one of the important factors in acquiring this condition.Over-the-counter treatmentPeople with freckles can go for over-the-counter products like AHA to  Read More

Ganglioside sialidase deficiency is also known as Sialoglycosphingolipids/ Mucolipidosis IV.They carry one or more than one sialic residue. This is a very rare metabolic disorder.It may arise due to a deficiency of transport channel receptor protein. If this disease becomes severe, it is called typical mucolipidosis IV; if it is mild and not that severe, it is called atypical mucolipidosis IV.Medication  Read More

Damaged tissue from gangrene cannot be saved. However, medication is available to help avoid gangrene from worsening. The sooner you receive therapy, the greater your chances of recovery.Gangrene treatment may comprise one or more of the following: Medication: Antibiotics are administered intravenously or orally to treat bacterial infections. To alleviate discomfort, pain medicines may be admini  Read More

The symptoms of PSEK usually develop shortly after birth or during the first year of life. Infants develop reddened plaques of thickened, rough and/or scaly skin, especially on the face, buttocks, arms and legs. Over time, these lesions can cover large areas of the body. The distribution of these lesions is almost perfectly symmetrical, meaning the size, shape and location of the lesions are extremely similar on both sides of the body. These p  Read More

Type 1 Classic Phenotype The signs and symptoms of males with the type 1 classic phenotype typically begin in childhood or adolescence (Desnick 2001, Desnick and Brady 2004). Symptoms increase with age primarily due to the progressive glycolipid accumulation in the micro-vascular system, kidney podocytes, and cardiomyocytes leading to kidney insufficiency and failure, heart disease, and/or strokes. Early and progressive clinical sympto  Read More

Chronic granulomatous disease (CGD) is a rare inherited primary immune deficiency disorder that affects certain white blood corpuscles (neutrophils, monocytes, macrophages, eosinophils). The disorder is characterized by an inability to resist repeated infectious diseases and a tendency to develop chronic inflammation. Life-threatening recurrent fungal and bacterial infections affecting the skin, lungs, and bones may occur along with swollen ar  Read More

Grover’s disease can usually be treated using topical medications, but sometimes requires oral medication, injections, or light therapy to treat it.Cortisone cream: Your dermatologist will prescribe you a cortisone cream if you have a small blister or outbreak that doesn’t itch.Tetracycline: If you have larger outbreaks that itch and cover the entire trunk, your dermatologist may prescribe the  Read More

The signs and symptoms of Gottron syndrome vary somewhat from one person to another. Because this condition is so rare, it is difficult to get a complete picture of the core features that define the syndrome. Generally, from birth-onwards, children with Gottron syndrome appear older than their actual age. The skin is unusually thin, taut, and parchment-like on the hands and feet (distal extremities) and may even involve the face. The h  Read More

Mutation in gene GL13 causes the disorders in the body from infancy collectively called Hall-Pallister Syndrome.It affects people with uneven development of many body parts of the body like extra fingers, toes, or skin between fingers.Diagnosis:The patient with HPS are infants, and the defects in their palms and toes are the prominent signs of diagnosing the disease. But to rule out the confusion  Read More

A genetic skin condition called hallopeau-siemens disease or dystrophic epidermolysis bullosa causes blisters to grow. One of the more severe types is the Hallopeau-Siemens syndrome type.Due to the defect's location in the dermis at the dermo-epidermal junction, even little skin trauma results in profuse blister production that always heals with scars.Anchoring fibrils are either absent or inadequate due t  Read More

A defect caused with birth that affects the skin and results in scaly, dry skin over the body is called Harlequin Fetus or Ichthyosis. It happens due to genetic mutations and wrong combinations in an infant’s body from parents.Difficulties in Children and Adults:Although the disease occurs in infancy, it is necessary to prepare for growing a child with this defect. These are the problems that could occu  Read More

Harley syndrome or Harlequin syndrome is a rare dysautonomic syndrome caused by the unilateral blockade of the T2-T3 fibers carrying sudomotor and vasomotor supply to the face.The autonomic nervous system is responsible for regulating the natural processes of the body, including sweating, skin flushing, and the response of the pupils to any stimuli. The exact cause of the condition is not found yet.The sym  Read More

The symptoms of AEC syndrome are highly variable, even among members of the same family. In addition, the small number of identified cases, the lack of large clinical studies, and the possibility of other genes or factors influencing the disorder prevent physicians from developing a completely accurate picture of associated symptoms and prognosis. Affected individuals or their parents should talk to their physician and medical team about their  Read More

Several over-the-counter or prescription medications are used to treat heat rash also known as prickly heat, sweat rash, or miliaria rubra.Ointments: Ointments like calamine lotions are recommended to treat the symptoms of heat rash, since calamine lotions have a number of benefits for the skin, partly because it contains zinc oxide. It helps treat heat rash by soothing itchiness. Take some calamine lotion in a cot  Read More

Usually, hematoma underneath the skin and within soft tissues such as muscles can be treated at home using the following methods:Elastic bandages help to keep swelling at bay.Elevating the affected area to alleviate swellingUsing ice packs multiple times each day for the first 24 to 48 hours to minimize swelling and soreness.Warm compresses after 2 days of ice to aid in the fluid's absorp  Read More

HS is divided into mild, moderate, and severe forms of the disease. Classification is based on the amounts of hemoglobin, reticulocytes, and bilirubin and the amount of spectrin in red blood cells. Hemoglobin transports oxygen in the blood. Reticulocytes are immature red blood cells. Bilirubin is formed in the liver when hemoglobin is broken down. Spectrin is a protein that helps keep the shape of a cell. Decreased hemoglobin and spectrin and  Read More

Angioedema or Hives is usually treated by avoiding known triggers to the allergic reaction.The prescription drugs for the treatments of hives and angioedema may include:Antihistamines: It is the standard treatment for hives and angioedema. These medications reduce itching, swelling and other allergy symptoms.Drugs that suppress the immune system: Drugs that can calm an overactive immune system  Read More

Human cowpox infection is a relatively uncommon zoonotic skin infection that is mostly found in European nations. Cowpox virus (CPXV) is a member of the Poxvirus family's Orthopoxvirus genus. Contrary to popular belief, most cowpox infections are spread to human beings by domesticated cats and rats. Rodents are cowpox's natural reservoir. Cows, cats, zoo animals, and humans are CPXV's unintentional hosts.Signs and  Read More

Ichthyosis Congenita is a type of genetic skin disorder that is very rare. It is also known as Harlequin ichthyosis or Keratosis Diffusa Foetalis. It happens to be in 1 person out of 3,00,000 births worldwide.This condition occurs in the child if either of the parents has this. If both the genes are defective, then the chances of birth of a child with ichthyosis congenita are in very severe form.There appe  Read More

A genetic disorder called harlequin ichthyosis is transmitted by autosomal recessive genes.No cure availableYour baby will need lifelong care for their condition once they are released from the NICU. They will need extensive daily care to exfoliate dead skin and keep their skin moisturized.After initial therapy, care becomes a critical component of the equation because there is no cure for Harl  Read More

Ichthyosis Hystrix Curth Macklin Type is an uncommon inherited skin condition. It is characterised by mild to severe scaling of the skin (ichthyosis). The scaly, thickened skin patches can range in severity from mild to severe and can develop on practically any portion of the body. Patches of excessively thick, hard skin can occur practically anywhere on the body in ichthyosis hystrix, Curth-Macklin type. Clinical experts have  Read More

KFSD is a type of ichthyoses, a group of inherited disorders of the skin in which the skin tends to be thick and rough and has a scaly appearance. Hardening of the skin around the hair follicles leads to scarring and baldness. This condition begins in infancy, initially appearing on the face and neck, and then progresses to the chest, back, abdomen, arms and legs. Hair loss of the eyebrows and scalp caused by the scarring become evident in chi  Read More

Ichthyosis Sjogren Larsson syndrome is an autosomal recessive defect in the gene that codes for the enzyme Fatty Aldehyde DeHydrogenase (FALDH).The gene defect leads to a deficiency of the enzyme. FALDH plays the role of oxidative metabolism of long-chain aliphatic aldehydes of fatty acids.Its deficiency causes the accumulation of fatty acids and alters cell membrane integrity skin, eyes, and central nervo  Read More

Ichthyosis Vulgaris is caused by an inherited genetic flaw, a mutation that affects a large protein called filaggrin.The faulty gene is inherited from one's parents and may be caused by one or more mutations in the profillagrin gene that occur early in fetal development.It is autosomal dominant, which means that all that is required for the condition is a single faulty copy of the gene that codes for f  Read More

Boys with X-linked ichthyosis appear normal at birth. The skin symptoms generally appear within the first year of life. Brownish scales that adhere to the skin are among the first signs of the disorder. The back and legs are most frequently involved early. The face, scalp, palms and soles, and hollows of the elbows and knees are usually spared. In about half of adult males, comma-shaped corneal opacities occur in the eyes (seen on exam  Read More

Ichthyosis Chanarin Dorman syndrome (CDS) is a rare autosomal disease that is also known as Ichthyotic Neutral Lipid Storage Disease with Ichthyosis (NSLDi). The mutations in the gene ABHD5 that is located on the short arm of chromosome 3.The gene encodes for a stimulating factor called the alpha-beta hydrolase domain, which is crucial for the enzyme Adipose TriGlyceride Lipase (ATGL).The primary role of A  Read More

Impetigo is a commonly transmitted skin infection. Bacteria such as Staphylococcus aureus and Streptococcus pyogenes infect the epidermis, or outer layers of the skin. The face, arms, and legs are the most commonly affected areas.Impetigo can affect anyone, although it is more frequent in children, particularly those aged 2 to 5.Minor cuts, bug bites, or a rash like eczema — any spot where the skin is damaged  Read More

Specific treatment for incontinentia pigmenti has not yet been described. However, the management of the disease requires a multidisciplinary approach and needs consultation with different specialists from time to time.Lesions appear within a few months from birth but disappear by adolescence. However, the lesions recur and require to be managed.All stage lesions must be kept cool and dry.The patients develop hypo  Read More

Medications or treatment for infantile sleep apnea will be decided by the doctor depending on the symptoms and their severity.Infants with sleep apnea can require breathing help from a machine or additional oxygen therapy. They might also require pharmaceutical therapy. These are all typically temporary solutions.Infant sleep apnea typically disappears as the child becomes older and more developed. By 40 w  Read More

Intertrigo is a rash that typically affects the creases of the skin, areas where the skin brushes together, or areas where the skin is frequently moist. This rubbing can create a breakdown in the skin's top layers, resulting in irritation and a rash.The disintegration of skin facilitates the development of germs or fungus in this location. It may aggravate the rash.Intertrigo is especially common in overwe  Read More

The most distinctive finding associated with hypomelanosis of Ito is characteristic skin changes. Most affected individuals develop areas that lack skin color (hypopigmentation). Any area of the body may be involved although the scalp, palms and soles are rarely affected. Skin changes may occur as patches, streaks or spiral-shaped (whorled) areas of discoloration and may affect one side of the body (unilateral) or both sides (bilateral). Affec  Read More

Similar to ringworm, jock itch is a common fungal ailment that is brought on by a fungus. An itching, stinging, burning rash appears on the skin of your groin, inner thighs, and butt crack as a result of a jock itch (gluteal cleft). Another name for jock itch is tinea cruris. Ringworm is also known as tinea, and the Greek word cruris signifies groin.Jock itch might persist for months if you don't address it. Ho  Read More

Johnson –stevens disease is a very rare syndrome with potentially fatal skin reactions in which loss of skin occurs and mucosal membranes accompanied by systemic symptoms is shown in some case. For these conditions, in 80% of cases, the reactions from medications are responsible.This condition requires intensive care or burn care unit in hospitalization,If a person is taking unessential medication  Read More

Some features of Kabuki syndrome are present at birth (congenital). Other features become apparent as an affected child ages. The specific findings and the severity of those findings can vary from one person to another. A wide variety of findings affecting multiple organ systems of the body can potentially occur. It is important to note that affected individuals may not have all of the features discussed below. Parents of an affected child sho  Read More

The following are keloids treatments. One or more ways may be appropriate for your scenario. Keloids can grow back, sometimes larger than before, even after effective flattening or excision. You might also create new ones.Wound healing: Compression dressings composed of elastic cloth or other materials may be used as the first treatment choice for newer keloids. This treatment is frequently used to remove keloids a  Read More

KID syndrome is present at birth. Nearly all cases have skin involvement, which includes red, rough, thickened plaques that are sometimes scaling, as well as sensorineural deafness or severe hearing impairment. Most patients develop eye findings, predominantly keratitis (superficial defects of the cornea), which may result in the eyes being very sensitive to light (photophobia), small blood vessels growing from the iris over the cornea  Read More

Pitted keratolysis is a skin illness that develops microscopic holes in your skin's top layer.It primarily affects the soles of your feet, but it can also affect your hands' palms.This condition's little holes or pits usually do not pain or itch, but they might become tender or irritating.They may also experience a burning feeling.These bacteria multiply at infection sites and  Read More

Haim-Munk syndrome is a rare genetic disorder characterized by the development of red, scaly thickened patches of skin on the palms of the hands and soles of the feet (palmoplantar hyperkeratosis), frequent pus-producing (pyogenic) skin infections, overgrowth (hypertrophy) of the fingernails and toenails (onychogryposis), and degeneration of the structures that surround and support the teeth (periodontosis). Periodontosis usually results in th  Read More

Keratosis Pilaris (KP), or chicken skin, is a skin disorder that appears as small bumps on the skin and is usually mistaken as goosebumps or small pimples.Keratin, i.e. proteins produced by the skin in large quantities, blocks hair follicles, and this leads to the development of red bumps on the skin.None can define why keratin is built up in keratosis pilaris. Itchiness and irritation can be felt on the s  Read More

Seborrheic keratosis is not harmful and does not require treatment. It can be removed if they irritate you.Seborrheic keratosis can be removed using one or more of the following techniques:Growth is being frozen: Cryotherapy (freezing a growth with liquid nitrogen) can be an effective technique to eradicate seborrheic keratosis. It does not usually work on thicker, elevated growths. This procedure carri  Read More

Latex allergy is an allergic reaction to specific proteins found in natural rubber latex, which is derived from the rubber tree. When People have a latex allergy, their body misidentifies latex as a potentially hazardous substance.Latex allergy can cause itchy skin, hives, and even anaphylaxis, a potentially fatal illness characterised by throat swelling and significant trouble breathing.The specialist can  Read More

Medications and other therapies may be used to alleviate itching, relieve pain, and improve healing in lichen planus. Therapy can be difficult. Consult your doctor to assess the potential advantages against any treatment adverse effects.Corticosteroids: Prescription corticosteroid cream or ointment is usually the first line of treatment for lichen planus. If it doesn't work and your disease is serious or spread  Read More

Lichen Urticatus is the most common childhood skin condition. It is distinguished by itchy and irritating red blotches or hives.It is caused by a hypersensitive allergic reaction to insect bites, drugs, food, plants, and prolonged sun exposure.Hives are characterized by raised red splotches that itch or burn and can range in size from small dots to large patches covering multiple areas of your body at the  Read More

Treatment for linear sebaceous nevus sequence is directed toward the specific symptoms that are apparent in each individual.The doctor may wait unless there are obvious deformities that need to be addressed.Pediatricians, neurologists, dermatologists, and other healthcare professionals may need to plan the treatment systematically and comprehensively.Therapeutic procedures and interventions specif  Read More

Lipoma is usually painless and harmful, but if it is bothering you, or growing further, then it needs to be removed.Lipoma treatments include:Surgical removal: Lipomas are mostly removed through surgery by cutting them out. However, there are chances that they may occur again. Since the surgery may leave a scar or get the area bruised, minimal excision extraction may be performed so that it results in l  Read More

Lobomycosis or Lobo disease is basically a bump in the skin, firm swellings, or malignant tumors.Infection occurs through traumatic implantation of the fungus into the skin.The symptoms of paracoccidioidomycosis generally occur from several weeks or months to years after the initial exposure to the fungus.The symptoms of Lobo disease vary according to which areas of the body are infected.  Read More

Localized Epidermolysis bullosa simplex (EBS) is a genetic disease, which means that it is caused by one or more genes not working correctly.The majority of EBS subtypes are inherited in a dominant manner. This means that an affected parent passes them on to half of his or her offspring. EBS affects both men and women equally.Epidermolysis bullosa simplex is often transmitted in an autosomal dominant manne  Read More

Malignant atrophic papulosis is an uncommon vasculopathy that affects the skin, gastrointestinal tract, and nervous system. The systemic variant has a rapid clinical course and a high death rate.TreatmentThere is no effective treatment for atrophic papulosis. Anticoagulants and blood perfusion drugs such as acetylsalicylic acid, pentoxifylline, dipyridamole, ticlopidine, and heparin have achieved partial regr  Read More

Melasma causes patches of discoloration. The patches are darker than your usual skin color. It typically occurs on the face and is symmetrical, with matching marks on both sides of the face. Other areas of your body that are often exposed to sun can also develop melasma. Brownish colored patches usually appear on the: cheeks forehead bridge of the nose chin It can also occur  Read More

Most persons with a strong immune system will not require treatment for molluscum contagiosum. These pimples normally go away on their own without the need for medical attention.A doctor can administer one of several successful molluscum contagiosum treatments. These are some examples:Cryotherapy: The doctor uses liquid nitrogen to freeze each bump.Curettage: small tools are used by specialists  Read More

Morgagni-Stewart-Morel syndrome is in-short, known as MSM syndrome.The exact cause of the disease is yet to be unraveled, and its manifestations are yet to be completely described.The disease was known to cause neurological manifestations.However, endocrinal and metabolic abnormalities have been found to be associated with the disease.The autosomal dominant genetic mutations have been bel  Read More

Mucha Habermann disease is a rare skin disorder, which is a part of a spectrum of disorders called Pityriasis Lichenoides Et Varioliformis Acula.Higher patient age, sepsis, systemic and mucosal involvement, and literature data of 119 FUMHD case reports, were four key unfavorable risk variables relating to a death result.Risk factorsThe affected persons develop hypersensitivity to infectious agents  Read More

Nail-patella syndrome (NPS) is a rare genetic disorder that is usually apparent at birth or during early childhood. Although the symptoms and physical characteristics associated with NPS may vary, characteristic abnormalities tend to include improper development (dysplasia) of the fingernails and toenails; absence (aplasia) and/or underdevelopment (hypoplasia) of the knee caps (patellae); underdevelopment of certain bones and/or webbing of ski  Read More

Necrotizing fasciitis (flesh-eating disease) progresses rapidly and can result in death hence an early diagnosis and providing appropriate treatment is of utmost importance.Early medical treatment is often presumptive; antibiotics should be started as soon as this condition is suspected.Surgical debridement is the standard treatment for necrotizing fasciitis.Aggressive Necrotizing fasciitis should  Read More

Non-scarring epidermolysis bullosa is a disease that results from mutations in KRT5 or KRT14 gene. These genes provide instructions for making a protein called keratin 5 and 14. There are two major types, and seventeen minor subtypes for this disease, all of which have common effects and symptoms.Among these, the four major subtypes of EBS are here:EBS-loc- in this, blisters are rarely present at birth and ma  Read More

Oculocutaneous albinism (OCA) is a group of rare inherited disorders characterized by a reduced amount or complete lack of melanin pigment in the skin, hair, and eyes. These conditions are caused by mutations in specific genes that are necessary for the production of melanin pigment in specialized cells called melanocytes. Absent or insufficient melanin pigment results abnormal development in the eyes resulting in vision abnormalities and ligh  Read More

Pityriasis rosea is a rash that often begins as an oval spot on the face, chest, abdomen or back. This is called a herald patch and may be up to 4 inches across. The patients suffering from this disease develop smaller spots that sweep out from the middle of the body in a shape that looks like drooping pine-tree branches. The rash can be itchy.usually, the symptoms and the condition settle down on their own without any m  Read More

Radiation disease doesn’t have any cure, but a few medications and therapy can extract some radiation from the body. People who are exposed to radiation should seek medical attention as soon as possible.The treatments for Radiation disease are as follows:DTPA (diethylenetriamine penaacetic acid): It binds to the radioactive elements present in the body, such as americium, plutonium, and curium. Fu  Read More

Radiation illness doesn’t have any cure, but a few medications and therapy can extract some radiation from the body. People who are exposed to radiation should seek medical attention as soon as possible.The treatments for Radiation illness are as follows:DTPA (diethylenetriamine penaacetic acid): It binds to the radioactive elements present in the body, such as americium, plutonium, and curium. Fu  Read More

Radiation sickness doesn’t have any cure, but a few medications and therapy can extract some radiation from the body. People who are exposed to radiation should seek medical attention as soon as possible.The treatments for Radiation sickness are as follows:DTPA (diethylenetriamine penaacetic acid): It binds to the radioactive elements present in the body, such as americium, plutonium, and curium.  Read More

Radiation syndrome doesn’t have any cure, but a few medications and therapy can extract some radiation from the body. People who are exposed to radiation should seek medical attention as soon as possible.The treatments for Radiation syndrome are as follows:DTPA (diethylenetriamine penaacetic acid): It binds to the radioactive elements present in the body, such as americium, plutonium, and curium.  Read More

Rapp-Hodgkin syndrome is a rare disease that is caused by a defect in genes. It can cause problems to hair, nails, skin, teeth, and sweat glands. The child may inherit one faulty gene from each parent and resulting in this syndrome.The child with Rapp-Hodgkin syndrome may have opened in the upper lip, skin erosions, fused eyelids, growth problems, hair loss, and other problems associated with appearance. him99999 U  Read More

Wiedemann-Rautenstrauch syndrome (WRS), also known as neonatal progeroid syndrome, is a very rare genetic disorder characterized by an aged appearance at birth (old man look) growth delays before and after birth (prenatal and postnatal growth retardation), and deficiency or absence of the layer of fat under the skin (subcutaneous lipoatrophy). It is anticipated that most individuals with WRS have decreased life expectancy. There are few indivi  Read More

Boys with X-linked ichthyosis appear normal at birth. The skin symptoms generally appear within the first year of life. Brownish scales that adhere to the skin are among the first signs of the disorder. The back and legs are most frequently involved early. The face, scalp, palms and soles, and hollows of the elbows and knees are usually spared. In about half of adult males, comma-shaped corneal opacities occur in the eyes (seen on exam  Read More

A hereditary genetic abnormality known as Riley-Day syndrome affects the neurological system of the human body.Dysautonomia, or injury to the autonomic nervous system, results in abnormalities in the autonomic nervous system, which links the brain and spinal cord to the muscles and produces autonomic dysfunction.The body might lose the ability to detect touch, smell, and pain as a result of certain disorde  Read More

Ringworm (tinea corporis) is a skin condition caused by a fungal infection, and no ringworm is involved in it. The name comes from the appearance of circular rashes on the skin.Here are simple cures and medications to treat ringworm.Topical antifungal: Over-the-counter antifungal creams kill the fungus and promote healing. Effective antifungal medications include miconazole, clotrimazole, and terbinafin  Read More

Signs and symptoms of rosacea may include: Facial redness. Rosacea usually causes a persistent redness in the central part of your face. Small blood vessels on your nose and cheeks often swell and become visible. Swollen red bumps. Many people who have rosacea also develop pimples on their face that resemble acne. These bumps sometimes contain pus. Your skin may feel hot and tender.  Read More

Rothmund-Thompson syndrome is a genetic condition inherited in an autosomal recessive manner.It has been discovered that two-thirds of people with RTS have RECQL4 gene mutation.This gene produces a protein involved in the replication and repair of DNA, the body's genetic material, whose holistic function is yet to be discovered.Since this gene does not show identifiable mutations in around one  Read More

Rothmund-thomson syndrome affects various parts of the body such as skin, teeth and hair, eyes, and bones.It is a genetic disorder developed by the mutation of the RECQL-4 gene and inherited through the autosomal recessive pattern( the child carries one affected gene from each parent).The infant affected by this syndrome develops a red, blistering rash on the face that may later spread to arms, legs buttoc  Read More

Scabies is a skin infestation caused by the Sarcoptes scabies or mites, that burrow into the skin and result in itchiness. If left untreated, it may result in chronic kidney and heart disease. Moreover, it is curable through medication.The cure and medication for scabies are as follows:Permethrin cream: A five percent permethrin cream is effective for killing mites and their eggs are burrowed deep into  Read More

Scalded Skin Syndrome (SSS) is a serious skin infection characterized by the peeling of skin over large parts of the body.This type of skin infection is caused by Staphylococcal aureus bacteria and can be treated as under:Oral Antibiotics: Antibiotics covering staphylococcus should be administered during early stages of infection. Cefazolin, Nafcillin or Oxacillin Antibiotics should be administered for methic  Read More

A common form of skin cancer on the middle and outer layers of skin is Squamous Cell Type. It is caused due to excessive exposure to Ultraviolet radiation, sunlight, or tanning beds or lamps.Cure/medications for Squamous Cell Type skin cancer:Meet the doctors and specialized dermatologists with the following details and information for the best possible treatment:Medical history of family and the  Read More

Skin tags are a skin growth in which a short soft skin hangs out of the body. These skin tags are painless and harmless and may grow on various sections of the body such as the eyelids, neck, chest, back, and stomach. The outer layer of skin tags might be irregular or smooth in appearance. They are frequently raised from the outer layer of the skin. They are typically skin shaded or brownish in color.Skin tags are  Read More

Stretch marks, medically known as striae, are seen as long, narrow, rippled marks that develop due to rapid stretching or shrinking of the skin. They can be red, brown, purple, black or pink in color. These marks can appear on any body part, but they are most common on stomach, upper arms, breasts, thighs, and lower back.Over-the-counter treatmentRetinol and Hyaluronic acid creams: People with stretch m  Read More

PXE results in a variety of signs and symptoms that vary in their number, type, and severity from person to person. Certain effects of PXE can cause serious medical problems, while others have less impact. Effects may include: skin changes, changes in the retina of the eye that may result in significant loss of central vision, changes in the cardiovascular system that may involve calcification of arteries and decreased blood flow in the arms a  Read More

Trichorhinophalangeal syndrome type ii is also known as Langer-Giedion syndrome. This is a very rare inherited disorder. This disorder affects multisystem parts of the body. It may result in thin hair, dystrophic nails, and small breasts.Some skeletal-related findings are short stature, short feet, radial deviation of the fingers, and marked hip dysplasia.Characterized by multiple osteochondromas and moder  Read More

The symptoms of PCT can vary greatly from one individual to another. Skin abnormalities characterize this disorder. Affected individuals are abnormally susceptible to damage of the skin from sunlight (photosensitivity). Extremely fragile skin that can peel or blister on minimal impact is common. Affected individuals may develop blistering skin lesions on areas of the skin that are frequently exposed to the sun such as the hands and face. These  Read More

Cholinergic urticaria is a common physical disorder of the immune system that is caused by increasing body temperature after exercise, intake of spicy foods, and mental stress. As a result of this, some small skin eruptions (hives) with well-defined borders and pale centers, surrounded by patches of red skin (wheal-and-flare reaction), appear for a few minutes. Sometimes it may be connected with fever and/or difficulty breathi  Read More

Physical urticaria is a subtype of urticaria that is caused by an extrinsic physical stimulus rather than occurring naturally. There are 7 subcategories of diseases that are classified as distinct diseases. Physical urticaria is considered to be unpleasant, itchy, and physically repulsive; it can last for months or years.Physical urticaria has no established aetiology, but it has been proposed that it is an autoimm  Read More

Vitiligo has no known cure. The purpose of medical therapy is to achieve a consistent skin tone by restoring colour (repigmentation) or removing the remaining colour (depigmentation).SurgerySkin grafts obtained from the patient: Skin is taken from one portion of the patient and utilised to cover another. Scarring, infection, and inability to repigment are all possible problems. it can also be called mic  Read More

Vitiligo Capitis is a condition that results in patchy loss of skin pigment. With time, the discoloured spots typically enlarge. Any portion of the body's skin might be impacted by the illness. The tongue and hair can both be impacted by it.Treatment or Cure available for the Vitiligo Capitis conditionThe type of treatment you receive will depend on your age, the location and amount of skin affected  Read More

Vulgaris type Ichthyosis is an inherited skin condition where the surface of your skin develops thick, dry scales from the accumulation of dead skin cells.Vulgaris type Ichthyosis, also known as fish scale disease or fish skin disease, can cause scales to develop from birth, but this is typically when they first do.Since they are easily mistaken for cases of severely dry skin, modest occurrences of Vulgari  Read More

Warts (common warts) is a viral disease that causes benign skin growths on different parts of the body.TreatmentCommon warts do not require treatment as they are resolved on their own after a few weeks or months.There are two main treatments:Salicylic acid: Salicylic acid gradually dissolves the hard scales upon applying it several times a day for over a few weeks. Most salicylic acid soluti  Read More

The symptoms of AEC syndrome are highly variable, even among members of the same family. In addition, the small number of identified cases, the lack of large clinical studies, and the possibility of other genes or factors influencing the disorder prevent physicians from developing a completely accurate picture of associated symptoms and prognosis. Affected individuals or their parents should talk to their physician and medical team about their  Read More

White Darier disease is also named as Keratosis Follicularis.It is a very rare skin disorder and is genetic.It is characterized by lesions on the skin that have thickened, rough bumps i.e., papules that appear greasy, yellow or skin color or brown crust.These lesions may spread and grow over time. This may vary from person to person. This mostly affects scalp, forehead, upper arms, chest, back, kn  Read More

Wiskott Aldrich syndrome is a syndrome that contains various conditions resulting from a mutation in WAS gene. Mutation in WAS gene results in a deficiency in WASP protein then platelet count starts decreasing. That is called thrombocytopenia. This disease is of immunological deficiency and reduced ability to form blood clots.In this disease, the problems like bloody diarrhea, recurrent infections, scaling, itchy s  Read More