Chanarin-Dorfman syndrome can affect many systems. All patients have skin findings that are usually present at birth: redness, fine scaling, dark pigmentation and severe itching which leads to scratching and skin-picking (excoriation). The skin appearance is referred to “ichthyosiform nonbullous erythroderma”. Patients also have liver disease with lipid storage which can lead to liver failure. About 60% of patients also have muscle  Read More

Deciduous skin is defined as the periodic, continuous, or seasonal peeling or shedding of the epidermal skin layer considering a generalized distribution.Deciduous skin is also referred to as the peeling skin syndrome (PSS), which is a rare autosomal recessive form of ichthyosis.This is clinically characterized by asymptomatic, superficial, and spontaneous peeling of the skin.It is also histologic  Read More

The first sign of Sjögren-Larsson syndrome is often preterm birth. Apparent at birth, the ichthyosis associated with SLS often starts as thickened skin that is yellow-brown in color (hyperkeratosis). This thickened skin eventually progresses to full scaling, especially at the neck, lower abdomen, and underarms, groin, and back of knees (flexures). Unique to SLS is the itchy characteristic of the skin (pruritis). The second feature  Read More

Ichthyosis hystrix, Curth-Macklin type is a rare autosomal dominant disorder characterized by dark hyperkeratotic plaques and palmoplantar keratoderma over knuckles, knees, and elbows.The causative mutations occur in the gene KRT1. The gene is responsible for the supramolecular assembly of keratin intermediate filaments.The histological examination of skin lesion biopsies diagnoses the disease through the  Read More

Chanarin-Dorfman syndrome can affect many systems. All patients have skin findings that are usually present at birth: redness, fine scaling, dark pigmentation and severe itching which leads to scratching and skin-picking (excoriation). The skin appearance is referred to “ichthyosiform nonbullous erythroderma”. Patients also have liver disease with lipid storage which can lead to liver failure. About 60% of patients also have muscle  Read More

Dry skin also known as xeroderma, is serious in patients with a history of comorbidities such as renal abnormalities, diabetes mellitus, hyperthyroidism, medications for the diseases, or occupational exposure to allergens/irritants.TreatmentThe aims of the treatment are rehydration, restoration of lipids in the epidermis, optimization of skin functions, and enhancement of skin differentiation.D  Read More

Newborns with Ichthyosis Netherton syndrome have Skin that is reddish (erythroderma) and occasionally has a thick, parchment-like skin covering. Scaly and R patches are predominant.Trichorrhexis, sometimes known as "bamboo hair," causes hair shafts to be brittle and break readily, resulting in short, sparse hair.The scaling may have a characteristic circular pattern in older kids and adults (icht  Read More

The first sign of Sjögren-Larsson syndrome is often preterm birth. Apparent at birth, the ichthyosis associated with SLS often starts as thickened skin that is yellow-brown in color (hyperkeratosis). This thickened skin eventually progresses to full scaling, especially at the neck, lower abdomen, and underarms, groin, and back of knees (flexures). Unique to SLS is the itchy characteristic of the skin (pruritis). The second feature  Read More

Haim-Munk syndrome is a rare inherited disorder characterized by the development of dry scaly patches of skin that are abnormally red and thickened on the palms of the hands and soles of the feet (palmoplantar hyperkeratosis). Such patches may appear around the age of one to five years. However, in some cases, hyperkeratosis may be present at birth (congenital). These reddened patches are usually confined to the undersides of the hands and fee  Read More

Recessive x-linked ichthyosis is a genetic skin disorder that results in extremely dry skin. Since it is a genetic disorder it is not curable, but the sign and symptoms can be controlled by the following methods.Skin softening cream and location: This disease is accompanied by fine or rhombus adherents' light gray or dark brown scaling on the skin. It can be treated with softening cream. These creams moisturize  Read More

Tinea versicolor signs and symptoms include: Patches of skin discoloration, usually on the back, chest, neck and upper arms, which may appear lighter or darker than usual Mild itching Scaling When to see a doctor See your doctor if: Your skin doesn't improve with self-care measures The fungal infection returns The patches cover large areas of your b  Read More