Cutis laxa is an inherited or acquired disorder of the skin, and connective tissue.The inheritance occurs in an autosomal recessive, dominant, or X-linked fashion.The causative mutations are in the genes for the synthesis of elastin and structural proteins of the extracellular matrix.Particularly, cutis laxa growth deficiency syndrome is characterized by growth and developmental delay and skeletal  Read More

Hypomelanosis of Ito is a rare condition characterized by distinctive skin changes, in which areas of the body lack skin color (hypopigmentation). These skin changes may present as patches, streaks or spiral-shaped (whorled) areas. In many cases, additional symptoms affecting areas outside of the skin also occur. There are a wide variety of symptoms potentially associated with hypomelanosis of Ito. Neurological findings such as seizures and de  Read More