ASTOR's primary purpose is to enroll families and patients with a history of Alport syndrome in a central registry.
The information we gather will be used as a basis for studies designed to ...

Condition: Alport Syndrome

Objective: In this study we will develop and apply imaging techniques to perform the first three-dimensional (3-D) measurements of brain biomechanics during mild head movement in healthy human subj ...

Condition: Healthy Volunteer

This phase I trial studies the side effects and best dose of lenalidomide and blinatumomab when given together in treating patients with non-Hodgkin lymphoma that has returned after a period of improv ...

Condition: Recurrent Burkitt Lymphoma

Interleukin-35 (IL-35), consisting of two subunits - Ebi3 and p35, is a pleiotropic anti-inflammatory cytokine implicated in fetal tolerance and pregnancy maintenance. Reduced IL-35 levels in abortion

Pathogenic variants in the PIK3CA gene, which encodes the p110-? catalytic subunit of the phosphoinositide 3-kinase (PI3K), are commonly associated with overgrowth syndromes and cancer. We report a pa

Ionizing radiation causes immune dysfunction, increasing susceptibility to infection and mortality. Extracellular cold-inducible RNA-binding protein (eCIRP) is released from cells during irradiation.